Differentiation on Demand: How Consumer Preferences Shape Product Variety in Hotelling Duopoly

Description
In this paper, a novel model of Hotelling duopoly is introduced that explains horizontal product variety as the result of consumer preferences, expanding on and meshing the works of Hotelling (1929) and Neven (1985). From this model, two opposing forces

In this paper, a novel model of Hotelling duopoly is introduced that explains horizontal product variety as the result of consumer preferences, expanding on and meshing the works of Hotelling (1929) and Neven (1985). From this model, two opposing forces from consumer preferences are found that impact the variety and price decisions of firms: market share revenues and price revenues. As firms face consumers with highly linear (weak) preferences over variety, the profit incentive is to simply capture the market by offering products that appeal to the middle consumer. However, as firms face consumers with highly quadratic (strong) preferences over variety, the profit incentive is to carve out and exploit a market segment by offering a distinct variety. Thus, observed product variety between minimal and maximal differentiation is emergent from consumer preferences, as firms face a balance of price and market share incentives.
Date Created
2024-05
Agent

Understanding Food Insecurity: An Analysis on Impacts and Solutions for Undergraduate Students at the ASU Tempe Campus

Description
The food-insecure population in the United States is significant, with a disproportionately large food insecure population being college students. Food insecurity is an issue of great concern not only because of the presence of malnourishment, but especially because of the

The food-insecure population in the United States is significant, with a disproportionately large food insecure population being college students. Food insecurity is an issue of great concern not only because of the presence of malnourishment, but especially because of the many negative effects on health it can have on individuals that come as a result of malnourishment. In addition to the many health issues that can arise, food insecurity has also been found to be correlated with poor academic performance in school which is especially important when it comes to the food insecure college student population. Among the many reasons that college students might be food insecure, one issue that is explored is that college students do not have the capabilities to prepare adequate meals for themselves, so their lack of ability to do so contributes to their food insecurity. One way to combat this issue is to encourage college students to take the initiative to learn how to cook meals. A survey evaluated the food insecurity status of undergraduate ASU students and explored various food habits such as meal preparation, fresh produce consumption, and various influencing factors and obstacles of eating healthy, among others. Results found that those who identified as food insecure were less likely to cook meals for themselves as often as those who are not food insecure, nor were they as likely to consume fresh produce as those who are not food insecure. Additionally, all students have reported improved academic performance and/or physical/mental wellbeing. With the support that eating healthy meals is important for college students’ academics and physical and mental wellbeing, as is having the knowledge on how to prepare healthy meals, a fresh produce resource guide was created with the purpose of encouraging ASU students to learn the basic skills of cooking and meal preparation.
Date Created
2024-05
Agent

Delivery of Alpha-Ketoglutarate from Hyaluronic Acid Hydrogels for Bone Repair Applications

Description
Bone loss affects millions of people every year posing a major public health problem. Currently, autograft and allograft bones are the only options for treating bone loss. Although, they pose many limitations including donor availability, immunogenicity risks, and the potential

Bone loss affects millions of people every year posing a major public health problem. Currently, autograft and allograft bones are the only options for treating bone loss. Although, they pose many limitations including donor availability, immunogenicity risks, and the potential to carry a risk of disease and/or infection transmission to name a few. Therefore, there is a pressing clinical need to create a novel treatment that will promote bone repair. Alpha-ketoglutarate (aKG) was investigated as it plays an important role in cellular energy metabolism as a key intermediate in the Krebs cycle. It has been shown to stimulate the production of collagen in the bone repair process. However, controlling the release of aKG is important in being able to control where and how much new bone growth is stimulated. To address this aKG was delivered via a hyaluronic acid hydrogel and its release was controlled via the degradation of poly(alpha-ketoglutarate) microparticles (paKG MPs). paKG MPs were synthesized and characterized based on size, shape, and uniformity. The release of aKG from paKG MPs was evaluated, as well as the addition of paKG MPs into norbornene functionalized hyaluronic acid and maleimide functionalized hyaluronic acid hydrogels. Initial cell work was also done to grow osteoblasts for future work. It was found that paKG MPs were of the desired size and shape. The release of aKG from the paKG MPs was found to be sustained. The addition of paKG MPs in norbornene functionalized hyaluronic acid (NorHA) was found to be ineffective due to the opaqueness of the MPs. Maleimide functionalized hyaluronic acid (MaHA) hydrogels were chosen as an alternative delivery system for this reason. Future tests will be done on the addition of paKG MPs into MaHA hydrogels. Osteoblasts were also successfully grown and will be used in future studies.
Date Created
2024-05
Agent

An Exploration of East Asian Americans in Film and Media: Renegotiating the Boundaries of Identity on Screen

Description
In this thesis, we identify and analyze several chosen themes of Asian American identity that we feel are touched on in interesting ways within the body of films and media we’ve chosen to focus on. We do not argue that

In this thesis, we identify and analyze several chosen themes of Asian American identity that we feel are touched on in interesting ways within the body of films and media we’ve chosen to focus on. We do not argue that these themes are the most important for all Asian Americans, but we do believe that these themes reflect some of the commonly discussed questions of Asian American identity, particularly within the mainstream middle class. In one vein, these themes underline desires and longing present within Asian America and parallel competing notions of exclusion and integration: dreams of success, belonging, and connection.
Date Created
2024-05
Agent

Challenges to College Nutrition: A Website to Bridge Resource Gaps

Description
This paper examines the multifaceted challenges surrounding college students' nutrition, with a specific focus on Arizona State University (ASU). Examining economic shifts, psychological influences, nutrition knowledge, and body image dynamics, it reveals the profound impact on students' food security and

This paper examines the multifaceted challenges surrounding college students' nutrition, with a specific focus on Arizona State University (ASU). Examining economic shifts, psychological influences, nutrition knowledge, and body image dynamics, it reveals the profound impact on students' food security and eating behaviors. Despite existing initiatives, persistent gaps in resources remain, necessitating comprehensive interventions to support students effectively. In response, "The Ultimate Health Resource for ASU Students," a website, was developed as an innovative solution. This platform aims to empower students by providing a centralized hub to access vital resources, connect with peers, and discover nutritious recipes. Proposed strategies encompass expanding food pantry offerings, developing mobile applications for nutritional guidance, and fostering partnerships with local organizations. By tackling these challenges head-on and fostering a culture of support, ASU can ensure that all students have equitable access to nutritious food options and the necessary resources to thrive academically and personally. The website serves as a place of empowerment, offering practical solutions and fostering a sense of community among ASU students striving for optimal health and well-being.
Date Created
2024-05
Agent

Determining the effect of immune checkpoint blockade on macrophages against Lewis Lung Carcinoma

Description
Immunotherapy uses the body’s immune system to find and terminate cancerous cells, and has revolutionized cancer treatment. However, in certain cancers, such as lung cancer, less than 50% of patients respond to treatment. This is in part due to the

Immunotherapy uses the body’s immune system to find and terminate cancerous cells, and has revolutionized cancer treatment. However, in certain cancers, such as lung cancer, less than 50% of patients respond to treatment. This is in part due to the immunosuppressive tumor microenvironment, which is composed of factors that promote tumor growth and proliferation. Tumor cells create a highly immunosuppressive microenvironment by triggering the anti-inflammatory phenotype of myeloid immune cells, which largely consist of tumor-associated macrophages (TAMs). Anti-PD-1 and anti-PD-L1 immune checkpoint blockade therapy helps promote the T cell anti-tumor response by releasing the brakes on cytotoxic T-cells. However, it is unclear how TAMs respond to these immune checkpoint antibodies. Our lab hypothesizes that blockade of the PD-1/PD-L1 signaling pathway drives a pro-inflammatory macrophage phenotype. This hypothesis is supported by data generated in the B16F10 murine melanoma model, but it is unknown whether macrophage response to PD-L1 blockade is generalizable to other tumor contexts. Thus, the goal of the project is to determine the impact of immune checkpoint blockade on murine macrophages in the Lewis Lung Carcinoma (LLC) model. Using Flow Cytometry, macrophage phenotypes will be analyzed to confirm whether a pro- inflammatory or anti-tumor response is generated.
Date Created
2024-05
Agent

A Meta-Analysis of the Literature on the Anti-Neoplastic Potential of Venom

Description
The objective of this meta-analysis is to holistically evaluate the existing body of literature on the anti-neoplastic potential of snake and bee venom. In recent years, venom-based therapeutics have emerged as a promising solution for combating cancer, generating a notable

The objective of this meta-analysis is to holistically evaluate the existing body of literature on the anti-neoplastic potential of snake and bee venom. In recent years, venom-based therapeutics have emerged as a promising solution for combating cancer, generating a notable rise in publications on the topic. Consequently, this comprehensive study aims to assess the current state of research and identify trends that may guide future investigations. Following the guidelines established by PRISMA, a total sample of 26 research papers were extracted from the electronic databases, PubMed and Scopus. These papers were categorized based on their publication dates, and research questions were formulated regarding three main topics: venom type, cancer-targeting mechanism, and cancer type. Statistical analysis of the research questions was performed using 2x2 contingency tables for a chi-square test. The results of the analysis reveal a statistically significant increase in publications focused on cell death mechanisms and breast cancer in recent years. This increase in publications reflects a growing interest in the potential for venom to induce apoptosis in cancer cells and target the unique biological properties of breast cancer. Overall, this meta-analysis offers insight into the evolving sphere of venom-based cancer research, providing a glimpse into the potential trajectory of this field.
Date Created
2023-12
Agent

Border Externalization and Migrants’ Rights in the Central Mediterranean: How The Italy-Libya Memorandum of Understanding Violates International Law and Destabilizes North Africa

Description

The deadly shipwrecks of migrant boats in the Mediterranean brought international attention to the plight of migrants in the mid-2010s but the focus soon shifted from humanitarian assistance to capturing smugglers and preventing migrants from reaching the shores of Europe.

The deadly shipwrecks of migrant boats in the Mediterranean brought international attention to the plight of migrants in the mid-2010s but the focus soon shifted from humanitarian assistance to capturing smugglers and preventing migrants from reaching the shores of Europe. The step towards a humane migration policy was a short-lived diversion from the project of “Fortress Europe” undertaken since the passing of the Schengen Convention. This project seeks to harden the external borders of Europe and prevent refugees from accessing the asylum system by enlisting neighboring non-European states to prevent migration at the point of departure. Deals such as the EU-Turkey deal of 2016 and the Spanish-Moroccan deals have resulted in migrants being funneled into increasingly dangerous corridors, such as Libya, as the safest and shortest paths are cut off. Although these deals are problematic in their own right, they pale in comparison to the egregious Italy-Libya Memorandum of 2017, which in practice enables Libyan militias to enforce Italy’s migration policy within the Libyan “rescue zone.” The human rights abuses perpetrated by these Libyan mercenaries in makeshift detention centers and on the Mediterranean are well documented, yet the Italian government continues to renew the deal and continue supplying these criminal groups. This literature review examines the issue of European border externalization in the Mediterranean and its impact on the internationally recognized rights of migrants and the stability of African governments. Using a systematic review of existing research, I analyze the key themes and trends that have emerged in the literature on this topic, including the legal and ethical implications of border externalization policies, the impact on African economies and governments, and the human rights implications for migrants. The review concludes that international courts are becoming increasingly ineffective in enforcing the rights of refugees and recommends a reform of the international refugee protection regime to favor autonomous movement.

Date Created
2023-05
Agent

Student and Teacher Perspectives on What Makes Students Successful in High School:
Evidence from Phoenix-area Schools

Description

Education is known for being powerful in reducing poverty, improving health, promoting healthier economies, and providing peaceful and productive opportunities for young people worldwide. It’s a key to success that has been threatened in the state of Arizona through low

Education is known for being powerful in reducing poverty, improving health, promoting healthier economies, and providing peaceful and productive opportunities for young people worldwide. It’s a key to success that has been threatened in the state of Arizona through low funding, teacher shortages, and a lack of resources. Inadequate learning environments further educational inequalities and hinder academic achievement among students. In finding a solution, the objectives of education policy in Arizona are analyzed from an economic and equity standpoint.

Date Created
2023-05
Agent

Career Information for Degrees in Statistics and Data Science

Description

Career information for degrees in statistics and data science according to frequently asked questions and twelve major categories of interest: arts, business, education, engineering, environment, government, law, medicine, science, social science, sports, and technology.

Date Created
2023-05
Agent