With aggregate background knowledge and best methodology practices from the literature review, this exploratory study seeks to further gather and advance knowledge on the subject of birthrate trends with respect to the economic conditions affecting the decisions to reproduce. The scope of the study particularly investigates the possible effects of the 2008 downturn of the economy and the concurring home mortgage crisis on birthrates in Arizona.

The Community Action Research Experiences (CARE) Program collaborated with the WellCare Foundation (WCF) to assess the referral sources of the clinic in order to more effectively reach additional potential patients. Archival data were analyzed from a 19-month period from the medical records of patients. Also, data were collected from interviews with the case manager of agencies that were a known referral source of WCF. These case manager interviews were completed over a one-month period. For the archival data part of the project, data were collected from 117 patients. Four representatives from community agencies participated in phone interviews. The results indicated that the most common referral sources were word of mouth, followed by community agency referrals. The results also indicated that WCF appears to have served a unique niche that is not served by other non-profit health clinics. These results led to implications for action and direction for future applied research.

This was a social movements analysis of the protests against Arizona's Senate Bill 1070, better known as the "Show Me your Papers" law. The project looked at the role religious organizations and religious leaders took in the protests as part of the immigration rights movement in Arizona. It was found that there were frames, networks, and resources already in place when SB 1070 passed in 2010. Rather than a movement emerging as a response to the legislation, it looked more like a social movement in crisis. The established frames, networks, and resources allowed this social movement to meet the challenge and have some measure of success in resisting and overturning SB 1070.

The Community Action Research Experiences program integrates the research and teaching mission of Arizona State University by providing services to the community by fostering professional and leadership development of students. It is hoped that the results of the collaborations with CARE will serve to further an organization's goals and effectiveness. VALLEYLIFE (VL) is a non-profit organization striving to help people with disabilities. VL develops Action Programs for each of its clients, whom they call members, to improve their independent or social skills. Examples of programs that members may work on include tasks such as computer training, visual arts, or writing. VALLEYLIFE lacked the data to evaluate if the developed and implemented Action Programs are properly carried out by the staff in ways that are beneficial to members. Given the problem, this research project sought to conduct a process evaluation of the staff regarding their implementation of the Action Programs. This involved observations of employee-member interactions in performing the Action Programs and an interview of staff measuring their preparedness and confidence in performing the program and their feelings of the programs and how things are run. This research provided the following implications to VALLEYLIFE. VL might consider performing periodic observations and reviews of the program implementation to monitor quality. VL may consider involving staff in program development and revision to create programs that better serve members. VL may consider generating ideas for how they may cooperate when a peer is struggling to keep up with events that happen through the day in the interest of better serving the members. Overall, employees are doing well as they are efficient in carrying out the written programs during program time. They are comfortable with what they are doing, use time effectively, and do their best to help the members. There is always room for improvement however and by considering some of the implications mentioned, VALLEYLIFE and their employees may be able to take action that may hold potential for further improvements in effectiveness.

As the student union on Arizona State University’s main Tempe campus, the MU should be a model of building sustainability. After a fire engulfed the MU’s second floor in 2007, the building underwent major renovations and achieved LEED v2.0: Commercial Interiors (LEED CI) Gold certification. Since then, more up-to-date building certification programs have been established, including the Green Globes (GG) green building rating system and a more recent version of LEED that suits the MU’s situation—Existing Buildings: Operations and Maintenance (LEED EB:OM). This paper performs a cost-benefit analysis of these rating systems, specifically looking at 1) national recognition, 2) ease of use, 3) amount of resources needed to invest, 4) length of time of the certification process, 5) certification fees and costs, 6) pre-requisites and system structure of point allotment, and 7) flexibility of the systems. A review of the previous LEED CI certification of the MU addresses 1) solar panel installation and renewable energy achievements, 2) improvement of indoor air quality, 3) application of sustainable construction practices, 4) missed opportunities since renovations were not performed on the entire building, 5) water efficiency scoring, and 6) lack of significant Energy & Atmosphere improvements. A proposal for the university to consider LEED EB:OM certification for the Memorial Union will be presented, analyzing the points already secured by campus-wide programs and policies, credits that are possible with minimal funding, and elaborating on opportunities already planned for completion, including 1) the Power Parasol project, 2) “Zero Waste by 2015” and “Carbon Neutrality” programs and goals, and 3) plans for alternative transportation methods through the Tempe Campus Access Management Plan. In conclusion, my recommendation to pursue LEED EB:OM and achieve Silver level will be presented. With the majority of LEED points already secured and several on the horizon, certifying the MU under LEED EB:OM will set an example and increase the amount of existing buildings on campus to pursue LEED certification. University-wide policies on green cleaning, sustainable purchasing, alternative energy sources, carbon neutrality, and LEED for Multiple Buildings all contribute to simplifying the LEED certification process for ASU buildings campus-wide.

Although discrimination is implicated in ethnic health disparities, social support may buffer against its negative effects on health. This study investigated whether prenatal maternal discrimination and social support would predict postpartum cortisol in low-income Hispanic women and infants. Among infants whose mothers reported high discrimination, low maternal social support was associated with high infant cortisol (ß= -0.293, p= 0.03). This provides evidence for the social buffering hypothesis.

The purpose of this study was to investigate: 1) within police departments in Maricopa County, exactly who helps the families left behind after a domestic homicide occurs? 2) What kind of short-term resources are offered by the police to immediately help the family and any children affected? And 3) are long-term services provided to the family and children of domestic homicide victims, and if not, to where is the family referred? To answer these questions, employees from each of the 14 city police departments in Maricopa County were interviewed. Participants answered a serious of both open-ended and scale questions either via email or over the phone. This study found that all police departments in cities of Maricopa County (with the exception of Litchfield Park, which is covered by the Sherriff's Office) have what is referred to as a Victim Services Unit. This is a small team comprised of social workers and other employees specifically trained to provide a continuation of support to victims from the crisis period through the investigative and judicial processes. In terms of services provided, this study found that most of the services offered to victims through police departments in Maricopa County are short-term in nature and fall under one of the following categories: On-scene crisis intervention and initial needs-assessments, immediate basic needs and referrals, financial resources, counseling, family advocacy centers, legal advocacy and assistance with the criminal process, or Child Protective Services. Results also indicated a positive relationship between city size and the amount of resources provided to victims after a homicide. Finally, in regards to long-term resources, this study found in general, all long-term needs are handled by social service agencies and non-profits, which victims are connected to by police departments after a needs assessment has been conducted. Based on these findings, a number of recommendations were made to Purple Ribbon Council, a domestic abuse prevention and supportive care non-profit that were designed to help Purple Ribbon Council increase its reach and effectiveness.

Cardiovascular disease (CVD) is the primary killer of Americans. As such, alternative means of a dietary approach to preventing or mitigating the development of CVD is clearly needed in addition to the ongoing recommendation for increased consumption of fruits and vegetables. Many studies suggest that fungi have the potential to decrease morbidity and mortality associated with CVD. Specifically, white button mushrooms, viz., Agaricus bisporus, are fairly common and inexpensive and full of untapped possibilities for efficacy although much additional research is needed. With antioxidants, e.g., selenium, and beta-glucans, viz., indigestible polysaccharides, white button mushrooms contain a plethora of bioactive ingredients that confer a potentially strong tool against the debilitating social impact of CVD.
The objective of this thesis was to establish protocols and a valid experimental design for testing whether dietary mushrooms could, in fact, be protective against CVD risk. Specifically, a case-study approach was used to validate this experimental method to test white button mushrooms and their impact on blood lipid levels and the inflammatory response. This dietary study involved preparation of two soups: a placebo, broth-based soup and one with one cup of white button mushrooms per cup of soup to provide one and a half cups of soup (and mushrooms) per day to each participant. The soup was prepared in The Kitchen Café at the ASU Downtown Campus (Phoenix, AZ).
After preparing the soup, the next goal was recruitment through listserv, local advertisements, flyers, and word of mouth of participants to test the overall plan. Over fifteen people responded; however, only one candidate met the inclusion criteria of someone at high risk of developing CVD and agreed to participate in the study. The participant visited the nutrition laboratory in downtown Phoenix (550 N. 5th Street). Anthropometric data and an initial blood draw were completed, and fourteen 1.5 cup containers of mushroom soup were dispensed to the participant. After two weeks, the individual returned and the same procedures were executed to include anthropometry and blood analysis. Even though the subject did not show changes in blood markers of CVD risk (lipids and inflammatory markers), the hypothesis for the thesis that the study design would be effective was accepted. Thus, the procedure was successful and validated and will be used in the future study.

Our goal was to design a method to express soluble folded major histocompatibility complex (MHC) proteins using human cell line HeLa lysate with the novel 1-Step Human In Vitro Protein Expression by Thermo Scientific in the presence of β2 microglobulin (β2m) and antigenic peptide.
We confirmed that the soluble protein MHC-A2.1 could be successfully attached to the Luminex magnetic beads and detected using the primary antibody anti-GST and the detection antibody goat mAb mouse PE. The average net MFI of the attached pA2.1-bead complex was 8182. Biotinylated A2.1 MHC complexes pre-folded with β2m and FLU M1 peptide (A2.1 monomers) were also successfully attached to Luminex magnetic beads and detected with BB7.2. The average net MFI of the detected A2.1 monmer-bead complexes was 318. The protein MHC complexes were multimerized on magnetic beads to create MHC tetramers and detected with BB7.2, PE labeled monoclonal antibody, via median fluorescent intensity with the Luminex platform. Varying protein, β2 microglobulin (β2m), and peptide concentrations were tested in a number of MHC-A2.1 protein refolding trials. Different antigenic peptides and attachment methods were also tested. However, none of the MHC-A2.1 protein folding and capture trials were successful. Although MHC-A2.1 complexes and recombinant MHC molecules could be attached to Luminex magnetic beads and be detected by Luminex arrays, soluble protein A2.1 could not be successfully expressed, refolded, captured onto Luminex beads, and detected. All refolding trials resulted in a net MFI of <25. The failed refolding and capture trials of A2.1 lead to the conclusion that human cell line HeLa lysate cannot be used to properly fold MHC molecules. However, efforts to refold the complexes onto Luminex magnetic beads are ongoing. We are also using the baculovirus expression system to refold soluble A2.1 lysate onto peptide-bead complexes.