Micro-Scale In Vivo Human Electrophysiological Functional Connectivity During Simple Language Production and Parkinson’s Disease

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Description
Information processing in the brain is mediated by network interactions between anatomically distant (centimeters apart) regions of cortex and network action is fundamental to human behavior. Disruptive activity of these networks may allow a variety of diseases to develop. Degradation

Information processing in the brain is mediated by network interactions between anatomically distant (centimeters apart) regions of cortex and network action is fundamental to human behavior. Disruptive activity of these networks may allow a variety of diseases to develop. Degradation or loss of network function in the brain can affect many aspects of the human experience; motor disorder, language difficulties, memory loss, mood swings, and more. The cortico-basal ganglia loop is a system of networks in the brain between the cortex, basal ganglia, the thalamus, and back to the cortex. It is not one singular circuit, but rather a series of parallel circuits that are relevant towards motor output, motor planning, and motivation and reward. Studying the relationship between basal ganglia neurons and cortical local field potentials may lead to insights about neurodegenerative diseases and how these diseases change the cortico-basal ganglia circuit. Speech and language are uniquely human and require the coactivation of several brain regions. The various aspects of language are spread over the temporal lobe and parts of the occipital, parietal, and frontal lobe. However, the core network for speech production involves collaboration between phonologic retrieval (encoding ideas into syllabic representations) from Wernicke’s area, and phonemic encoding (translating syllables into motor articulations) from Broca’s area. Studying the coactivation of these brain regions during a repetitive speech production task may lead to a greater understanding of their electrophysiological functional connectivity. The primary purpose of the work presented in this document is to validate the use of subdural microelectrodes in electrophysiological functional connectivity research as these devices best match the spatial and temporal scales of brain activity. Neuron populations in the cortex are organized into functional units called cortical columns. These cortical columns operate on the sub-millisecond temporal and millimeter spatial scale. The study of brain networks, both in healthy and unwell individuals, may reveal new methodologies of treatment or management for disease and injury, as well as contribute to our scientific understanding of how the brain works.
Date Created
2021
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Distortion Robust Biometric Recognition

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Description
Information forensics and security have come a long way in just a few years thanks to the recent advances in biometric recognition. The main challenge remains a proper design of a biometric modality that can be resilient to unconstrained conditions,

Information forensics and security have come a long way in just a few years thanks to the recent advances in biometric recognition. The main challenge remains a proper design of a biometric modality that can be resilient to unconstrained conditions, such as quality distortions. This work presents a solution to face and ear recognition under unconstrained visual variations, with a main focus on recognition in the presence of blur, occlusion and additive noise distortions.

First, the dissertation addresses the problem of scene variations in the presence of blur, occlusion and additive noise distortions resulting from capture, processing and transmission. Despite their excellent performance, ’deep’ methods are susceptible to visual distortions, which significantly reduce their performance. Sparse representations, on the other hand, have shown huge potential capabilities in handling problems, such as occlusion and corruption. In this work, an augmented SRC (ASRC) framework is presented to improve the performance of the Spare Representation Classifier (SRC) in the presence of blur, additive noise and block occlusion, while preserving its robustness to scene dependent variations. Different feature types are considered in the performance evaluation including image raw pixels, HoG and deep learning VGG-Face. The proposed ASRC framework is shown to outperform the conventional SRC in terms of recognition accuracy, in addition to other existing sparse-based methods and blur invariant methods at medium to high levels of distortion, when particularly used with discriminative features.

In order to assess the quality of features in improving both the sparsity of the representation and the classification accuracy, a feature sparse coding and classification index (FSCCI) is proposed and used for feature ranking and selection within both the SRC and ASRC frameworks.

The second part of the dissertation presents a method for unconstrained ear recognition using deep learning features. The unconstrained ear recognition is performed using transfer learning with deep neural networks (DNNs) as a feature extractor followed by a shallow classifier. Data augmentation is used to improve the recognition performance by augmenting the training dataset with image transformations. The recognition performance of the feature extraction models is compared with an ensemble of fine-tuned networks. The results show that, in the case where long training time is not desirable or a large amount of data is not available, the features from pre-trained DNNs can be used with a shallow classifier to give a comparable recognition accuracy to the fine-tuned networks.
Date Created
2018
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