Relationship Between Physical Activity, VLDL Lipoproteins, and T2DM Risk in Obese Latino Youth
Description
The purpose of this study was to examine the association between VLDL and diabetes risk factors, and the impact of a lifestyle intervention on VLDL levels in obese Latino youth. Participants (N=160) in this study were taken from a lager diabetes prevention program for Latino adolescents (Age=14.8±0.8 years, BMI=98.2±1.4). Youth participated in a 12-week lifestyle intervention that included physical activity (60 minutes, 3x/week) and nutrition education sessions (60 minutes, 1x/week) that were delivered to families at the downtown Phoenix YMCA. Primary outcomes included VLDL and diabetes risk factors including fasting and 2-hour glucose and insulin which were measured at baseline and 12-weeks post-intervention. Baseline VLDL levels were significantly correlated with fasting insulin (r =.270, P<0.01) and youth who were more insulin resistant displayed higher VLDL levels compared to youth who were less insulin resistant derived from fasting insulin levels (M=29.8±14.7 mg/dl vs. M=21.6±9.6 mg/dl, P<0.01). In total, 77 participants completed the lifestyle intervention. At post-intervention, VLDL levels were significantly reduced (M=26.0±13.3 mg/dl to M=23.3±11.6 mg/dl, P=0.02). Culturally-grounded, community-based, family-focused lifestyle interventions are a promising approach for reducing cardiovascular disease risk factors in high-risk youth at risk for diabetes.
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2018-12
Agent
- Author (aut): Navabi, Neeku Ariana
- Thesis director: Shaibi, Gabriel
- Committee member: Soltero, Erica
- Committee member: Ryder, Justin
- Contributor (ctb): School of Nutrition and Health Promotion
- Contributor (ctb): Arizona State University. College of Nursing & Healthcare Innovation
- Contributor (ctb): Barrett, The Honors College