The purpose of this lecture-recital is to explore the Protestant Reformation’s effect on the lives of a selected number of composing organists who were active in the field of church music before, during, and after the Reformation. The organists were selected based on the prominence of their positions and the significance of their compositions in the history of the organ. The lecture thus focuses on their employment situations and the repertoire they created. Jan Pieterszoon Sweelick is one of the most extreme examples of changed employment due to the Reformation. Trained as a Catholic organist, and taking up his position at the Oude Kerk Amsterdam at the age of 19, Sweelinck was forced to adapt quickly when the city converted to Calvinism within that same year. He became the civic organist, playing daily recitals on the organ instead of liturgical music, which was prohibited by the Calvinists. Because of his background in music and his compositional inclinations, Martin Luther created a liturgy that was much friendlier to musicians than was that of Calvin. Lutheranism fostered many fine organist-composers, culminating in the music of J.S. Bach. Early in the Reformation, Hans Kotter was fired from his position in Catholic Fribourg due to his Protestant leanings. Samuel Scheidt also suffered because of religious turmoil. He published three extraordinary volumes of organ music, entitled Tabulatura nova, in 1624, but the onset of the Thirty Years War cost him his employment. His final compositions are simple chorale harmonizations, reflecting the upheaval of the Reformation and the War. In Catholic Italy and Spain, where Reformers never gained a strong foothold, Marco Antonio Cavazzoni and Antonio de Cabezón were able to continue their work with little change. Due to the nature of their work and instruments, organists stand at the nexus of religion, economics, politics, and art. This lecture-recital seeks to reveal these relationships following the Reformation. These significant organist-composers provide case studies for how the changing religious and political climates of the Reformation affected the work of organists and the music they composed.