I present a trade-study of methods for a 1-port vacuum cryogenic in-situ calibration of a vector network analyzer. The three main methods I investigated in this work were: calibration using a commercial off the shelf latching electro-mechanical six way switch, a custom switch board, and a flexible multi channel stripline based printed circuit board. The test procedure was developed for use in a ground based closed-cycle cryogenic test bench to measure the reflection coefficient of a single port connectorized device under test. The device was installed in the cryogenic system alongside calibration standards. The goal of the trade study was to find which method could be used to accomplish calibration and device measurement in a single thermal cycle. Four cycles were required for industry standard open-short-load device calibration. Room temperature measurements were done with all three calibration schemes but ultimately only the single pole six throw switch proved effective enough for further testing. The cryogenic testing was carried out on an arbitrary device at ∼ 3K temperature, over a 6 GHz bandwidth. The final objective was to develop a setup and procedure for measuring the frequency and temperature dependent complex impedance of superconducting devices such as hot electron bolometer mixers, which are used for down converting the signal in the IF chain of astronomy instruments. Characterization of superconducting devices while they are at their operating temperature is challenging using traditional calibration methods. This commercial alternative is less expensive and more efficient in terms of thermal cycles and set up because it can be installed in a wide variety of cyrogenic systems.

Studying the interstellar medium (ISM) is the key to answering questions about how material that exists between the stars drives the evolution of galaxies. Current models for the ISM life-cycle exist, but several steps lack observational evidence. Inthis dissertation I present the work I completed in support of up-coming mission to further study the ISM. This work includes ancillary data analysis of the Carina Nebula for the upcoming balloon mission: astrophysics stratospheric telescope for high spectral resolution observations at submillimeter wavelengths (ASTHROS). I present a derived molecular gas map of Carina from Herschel dust continuum emission maps at wavelengths between 70-500 microns. I compare it to the distribution of atomic gas, using HI 21 cm data, and of multiple CO isotopologues for the J = 1 → 0 rotational transition. I use these data sets to separate the CO–dark and CO–bright molecular components to study their relative contribution to the total molecular gas mass budget in Carina. I studied the transition between atomic and molecular gas in this region, by deriving the molecular fraction as a function of position, and comparing it to theoretical models of this transition. I also present the flight hardware design, testing, and space qualification of the intermediate frequency (IF) harness for the galactic/extragalactic ultra long duration balloon spectroscopic terahertz observatory (GUSTO). The harness transmits signal via novel cryogenic flexible stripline based transmission lines operating from 0.3 - 6.0 GHz. I designed three sets of 8-channel ribbons with characteristic insertion loss of 3.07 dB/ft at 5 GHz while the line was at a temperature gradient between 20 K - 300 K. Missions like GUSTO make use of non-linear mixing elements to achieve down-conversion of higher frequencies into IF bands. The mixers have a temperature dependent impedance that is difficult to measure. The last chapters of this work detail my attempt to carry out in-situ vacuum cryogenic calibrations using industry standard commercial off-the-shelf calibration kits and cryogenic RF electro-mechanical latching switches. I present the complex impedance of a non-linear superconducting transmission line as measured with a cryogenic calibration.