The objective of this project was to complete an in-depth design study for the creation of a prophylactic knee brace. Background literature research analysis demonstrated that soft tissue injuries of the knee were the most prominent injuries related to the knee joint. The literature exhibited that the leading injury of the knee joint consisted of ACL lesions and meniscal tears. Utilizing the information obtained, it was determined that the objective of the knee brace was to emphasize prophylaxis of soft tissue injuries. As such, further analysis was performed in order to analyze injury mechanisms and knee joint biomechanics that would be relevant in injury prevention. An epidemiological review was also conducted regarding current braces that existed in the market today. These results were accounted for when formulating a novel design for the prophylactic device. The key feature of the brace is the implementation of shear-thickening fluid, a non-Newtonian fluid that is able to exhibit fluid-like properties at rest and solid-like properties when impacted by an outside force. This unique property is ideal for a knee brace for its enhanced adaptability and protective effects. A three dimensional digital prototype was designed in a SolidWorks software as the final result. Future endeavors consist of developing a physical prototype and conducting stress and strain analysis of the device in addition to testing its efficacy in human trials. After completion of testing and necessary revisions the goal will be to patent the technology and commercialize the brace into a device available on the public market.