Light-induced CO2 Reduction By Cobalt-cytochrome b562: Rational Design and Directed Evolution Approaches
Description
The successful reduction of CO2 and protons by a light-induced cobalt porphyrin/cytb562 hybrid metalloenzyme in water is reported. Incorporation of the porphyrin into a protein scaffold results in increases in CO and H2 production over naked porphyrin. Rational point mutations to the CoPPIX binding site of cytb562 modulate production, indicating possible further improvements in catalytic activity.
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2020-05
Agent
- Author (aut): Gwerder, Noah D
- Thesis director: Ghirlanda, Giovanna
- Committee member: Williams, Peter
- Committee member: Mangone, Marco
- Contributor (ctb): School of Molecular Sciences
- Contributor (ctb): Barrett, The Honors College