The Exploration of Neuroticism as a Mediating Mechanism Between Trauma & Alcohol Related Problems

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Description

Eysenck’s (1967) biological model of personality suggests traits relate to meaningful functioning and structural variations regarding cortical and limbic brain regions. Neuroticism denotes the tendency to experience negative affect (i.e. anxiety, worry, tension, irritability) more frequently than others do (Eysenck

Eysenck’s (1967) biological model of personality suggests traits relate to meaningful functioning and structural variations regarding cortical and limbic brain regions. Neuroticism denotes the tendency to experience negative affect (i.e. anxiety, worry, tension, irritability) more frequently than others do (Eysenck 1956). Patock-Peckham & Lopez, 2010). Individuals higher on neuroticism have lower thresholds for a fight or flight response to stressors (Xin et al., 2017). Childhood trauma is associated with increased expression of neurotic traits in an alcohol dependent sample (Schwandt et al, 2013). However, to date, it remains unexplored in the existing literature as to whether or not neuroticism mediates any indirect links from facets of childhood trauma (e.g. emotional, sexual, physical, or neglect) or a supportive family on dysregulated drinking. Impaired control over alcohol use reflects drinking larger amounts and for greater periods than one originally intended (Heather et al., 1993). We fit a multiple-group structural equation model with 937 (465 women/472 men) university student volunteers on a model from trauma facets to alcohol use and problems with neuroticism and impaired control as potential mediators. Results: We found that higher levels of emotional abuse were directly linked to more neurotic symptoms among both cisgender sexes. In addition, we found that higher degrees of a supportive family were directly linked to less neuroticism among women only. Interestingly, neuroticism was directly linked to less alcohol use. Yet, when impaired control was a mediator of the neuroticism to alcohol use pathway, alcohol use increased. We also found that higher levels of supportive family were indirectly linked to less neuroticism and in turn, less impaired control over drinking among women only. However, higher levels of emotional abuse were indirectly linked to more alcohol-related problems through both more neuroticism and impaired control for both genders. Our results support that impaired control may be a key mediating mechanism to internalizing traits such as neuroticism in the alcohol use quantity/frequency pathway. Further, our results suggest that emotional abuse may be an important therapeutic target of intervention for those with comorbid internalizing and alcohol use disorders. NIH/NIAAA K01AA024160-01A1; Burton Family Foundation FP11815 to Julie Patock-Peckham.

Date Created
2021-12
Agent

The direct & indirect links from facets of childhood trauma to arousability, impaired control, alcohol use, & alcohol-related problems.

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Description

Hyper-arousal theory presumes that experiencing trauma can increase one’s sense of fight or flight responses or generalized sense of arousability (Riemann et al., 2010). While this theory has been examined in studies regarding insomnia (e.g. Schwandt et al., 2013) it

Hyper-arousal theory presumes that experiencing trauma can increase one’s sense of fight or flight responses or generalized sense of arousability (Riemann et al., 2010). While this theory has been examined in studies regarding insomnia (e.g. Schwandt et al., 2013) it has yet to be examine with dysregulated drinking outcomes such as impaired control over alcohol use. Impaired control over alcohol use (IC) reflects drinking beyond one’s own self-proscribed limits for one’s own drinking behaviors (Heather et al., 1993). According to multiple review papers on the topic (Leeman et al., 2012; 2014), IC is an understudied topic regarding alcohol use disorders (AUDs). Thus, we sought to explore a pathway from facets of childhood trauma (emotional, physical, & sexual abuse, & neglect) versus a supportive family to arousability to drinking outcomes (i.e. IC, alcohol use, & alcohol-related problems). Method: We fit a multiple-group structural equation model with 835 (368 women/ 467 men) university student volunteers. As our model failed the overall invariance test, χ2Δ (20 df) = 55.788, p < .001, we allowed our hypothesized model to moderate on sex. Results: The direct link from sexual abuse to both IC and alcohol-related-problems was stronger for men than women. Emotional abuse was directly linked to higher levels of arousability among women, whereas an emotionally supportive family was related to lesser degrees of arousability among men. Impaired control mediated the indirect link between higher levels of arousability and alcohol use for both sexes. Impaired control also mediated the indirect link between physical neglect and alcohol-related problems among both sexes. Higher levels of emotional abuse were indirectly linked to both more alcohol use & problems through increased arousability and in turn, more IC among women. Higher levels of sexual abuse were indirectly linked to more alcohol problems through higher degrees of impaired control among men. Conclusions: We found evidence in favor of the Hyper-arousability Theory regarding dysregulated drinking with a direct link between arousability and IC. While physical neglect appears to affect both sexes drinking behaviors, emotional abuse may play a stronger role for women than men, while sexual abuse may play a stronger role among men.

Date Created
2021-12
Agent

Animal Assisted Activities: An Experimental Comparison Study of Therapy Dogs versus Massages to Alleviate Short-Term Stress

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Description
Animal assisted activities and therapy have demonstrated efficacy but the question remains of whether the animals themselves are the mechanism of change or if other factors mediate this relationship. We investigated novelty and touch as mediators between therapy dogs and

Animal assisted activities and therapy have demonstrated efficacy but the question remains of whether the animals themselves are the mechanism of change or if other factors mediate this relationship. We investigated novelty and touch as mediators between therapy dogs and stress reduction as no other study has done both. Additionally, we were interested in whether the belief that a treatment is relaxing or simply providing a break acted as mediators. We explored these relationships using three conditions: therapy dog interaction, massage, and no-treatment control. Interacting with a therapy dog is similar to receiving a massage in each of the mediators of interest. Thus, should the therapy dogs outperform the massage in relieving stress, it suggests something there is something unique about the dogs themselves, beyond the mediators held constant for both the therapy dog and massage condition. We included the no-treatment control to determine whether treatment at all was effective in reducing stress. We tested 40 participants aged 18 to 43 years old over the course of three days. Participants were measured pre-treatment using two self-report surveys of stress, the Stress Overload Scale- Short (SOS-S) and the Stress Appraisal Measure (SAM) as well as a physiological indicator of stress, heart rate variability (HRV) measured by the Scosche Rhythm24 Waterproof Armband Heart Rate Monitor. Participants were randomly assigned to a condition for seven minutes. Afterwards, all measures were readministered. We found no significant interaction of time on condition nor any main effect of condition on any of the measures. However, we found significant main effects of time on both subscales of the SOS-S and the threat, centrality, controllable-by-others, and stressfulness subscales of the SAM. We are unable to determine whether there is a unique benefit of therapy dogs themselves but overall, the event was effective in reducing stress as reported by the participants. We recommend continued investigation of mediators in animal assisted activities and therapy.
Date Created
2019-12
Agent

Developing and Testing an Intervention to Promote Future Self-Connectedness Among Premedical Students

Description
This study was designed to develop and test an intervention to increase future self-connectedness among students considered on the pre-medical career path at Arizona State University. Recent research has identified organic chemistry as one primary reason pre-med students change their

This study was designed to develop and test an intervention to increase future self-connectedness among students considered on the pre-medical career path at Arizona State University. Recent research has identified organic chemistry as one primary reason pre-med students change their major during undergraduate studies. Difficulty connecting to one’s future self and low academic self-efficacy are also reasons that help explain the large numbers of students changing majors. This study proposed and tested an intervention to increase future self-connectedness in order to help keep students in the pre-med pathway. It was predicted that the proposed intervention would be successful at promoting greater future self-connectedness and academic self-efficacy across all students, with significant results hypothesized for women and members of minority groups. It was further hypothesized that this intervention would be successful at decreasing stress levels and increasing persistence when given sample MCAT questions. 78 undergraduate participants from organic chemistry classes completed this study, 37 in the intervention and 41 comprising the control group. The intervention consisted of a guided thought exercise that walked participants through a day in the life of a medical resident. Results were found indicating a significance between the mean scores for the intervention group and increased future self-connectedness, as well as academic self-efficacy as compared to the control. Results also indicate that lower levels of initial future self-connectedness and academic self-efficacy were associated with higher levels of change in levels of future self-connectedness following the intervention. Additionally, high initial academic self-efficacy was correlated with lower levels of perceived stress and higher overall grade point average, as hypothesized. Results indicate that the intervention was successful at increasing future self-connectedness and academic self-efficacy among pre-med students, especially among women and minority groups, however the intervention was not successful at decreasing levels of perceived stress within the intervention group. Given the small sample size future studies are needed to further verify the generalizability of these results.
Date Created
2019-05
Agent

The Exploration of Depression as a Mediating Mechanism between Trauma and Alcohol Problems

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Description
Introduction: Depression is one of the most prevalent mental illnesses in the United States, and is characterized by feeling sad or empty most of the day, nearly every day (American Psychiatric Association, 2013). The experience of childhood trauma is one

Introduction: Depression is one of the most prevalent mental illnesses in the United States, and is characterized by feeling sad or empty most of the day, nearly every day (American Psychiatric Association, 2013). The experience of childhood trauma is one of many factors that may lead to depression, while trauma can also yield other adverse life outcomes, such as alcohol-related consequences (Felitti et al., 2001; Neumann, 2017). One of the specific aims of this investigation was to examine the direct influences of childhood trauma on depression. We also examined selected direct and indirect influences of childhood trauma on drinking outcomes through the potential mediating mechanism of depression. We examined three distinct drinking outcomes, 1) impaired control over drinking (i.e. the inability to stop drinking when intended), 2) heavy episodic drinking (four or more drinks on one occasion for men, four or more for women), and 3) alcohol-related problems. Methods: A survey was administered to 940 (466 women, 474 men) university students. Structural equation modeling was used to examine the data. Potential two- and three-path mediated effects were examined with the bias corrected bootstrap technique in Mplus (MacKinnon, 2008). Results: Emotional abuse was found to be positively associated with depression. In contrast, having an emotionally supportive family was found to be negatively associated with depression. Congruent with the Self-Medication Hypothesis, depression was found to be positively associated with impaired control over drinking. Physical neglect was found to be positively associated with impaired control. Lastly, emotional abuse was found to be indirectly linked to increased heavy episodic drinking and alcohol-related problems through depression and impaired control.
Date Created
2018-12
Agent

Correlates of Cannabis Vape-Pen Use and Knowledge Among U.S. College Students

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Description

Introduction: The proliferation of electronic devices, such as vape-pens, has provided alternative means for cannabis use. Research has found cannabis-vaping (i.e., vape-pen use) is associated with lower perceived risks and higher cannabis use. Knowledge of these products may increase likelihood of

Introduction: The proliferation of electronic devices, such as vape-pens, has provided alternative means for cannabis use. Research has found cannabis-vaping (i.e., vape-pen use) is associated with lower perceived risks and higher cannabis use. Knowledge of these products may increase likelihood of subsequent use. As policies for cannabis shift, beliefs that peers and family approve of this substance use (injunctive norms) increase and there has been an increase in vape-pen use among young adults (18–35 year olds); however, correlates thereof remain unknown. Young adults often engage in cross-substance use with cannabis and alcohol, making alcohol a potential correlate of cannabis vape-pen use and knowledge. Therefore, we examined alcohol use and other potential correlates of vape-pen use and knowledge among a sample of university students.

Methods: This secondary data analysis utilized surveys at multiple colleges in the U.S. (N = 270). Alcohol use, social anxiety, cannabis expectancies, injunctive and descriptive norms and facets of impulsivity were examined as correlates of vape-pen use and knowledge using bivariate correlations and logistic regressions.

Results: Alcohol use was correlated with cannabis vape-pen use and knowledge. Frequency of cannabis use, peer injunctive norms, and positive expectancies were associated with increased likelihood of vape-pen use. Lack of premeditation, a facet of impulsivity, was associated with cannabis vape-pen knowledge.

Conclusions: Given the unknown nature and consequences of cannabis vape-pens, the present findings offer valuable information on correlates of this behavior. Further, correlates of knowledge of vape-pens may point to areas for education and clinical intervention to prevent heavy cannabis vape-pen use.

Date Created
2017-11-21
Agent

The Effect of Work-Life Balance on Subjective Well-Being and Social Support in Midlife

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Description
Understanding work-life balance is crucial for improving the work environment, managing work and personal demands, and maintaining well-being. However, scientific literature regarding work-life balance has not adequately investigated its long-term relationships with subjective well-being and social support factors. Up to

Understanding work-life balance is crucial for improving the work environment, managing work and personal demands, and maintaining well-being. However, scientific literature regarding work-life balance has not adequately investigated its long-term relationships with subjective well-being and social support factors. Up to this point, empirical research uses cross-sectional or short-term longitudinal data and is focused on broad outcomes related to work-life balance. The current study adds to the literature by breaking down work-life balance into work interference, how work experiences negatively contribute to personal life, and work enhancement, how work experiences positively contribute to personal life. Work-life balance factors will be explored with relationships between three components of subjective well-being: positive affect, negative affect, and life satisfaction. Additional examined relationships are between work-life balance factors and quality of social support through positive and negative relationships with spouse, family, and friends. Finally, the relationships with work-life balance are examined with potential covariates. The research questions will be tested with multilevel models using data collected from 2006 \u2014 2014 from the Health and Retirement Study, a longitudinal panel survey of participants in midlife and old age. In short, work enhancement is predictive of the level and change in life satisfaction and positive factors; work interference is predictive of the level and change in negative factors. The discussion focuses on understanding the directionality of the relationships and how future research can build upon the understanding of subjective well-being and social support.
Date Created
2016-12
Agent

Comparison of Regression and Tree Analyses for Predicting Alcohol-Related Problems

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Description
Problems related to alcohol consumption cause not only extra economic expenses, but are an expense to the health of both drinkers and non-drinkers due to the harm directly and indirectly caused by alcohol consumption. Investigating predictors and reasons for alcohol-related

Problems related to alcohol consumption cause not only extra economic expenses, but are an expense to the health of both drinkers and non-drinkers due to the harm directly and indirectly caused by alcohol consumption. Investigating predictors and reasons for alcohol-related problems is of importance, as alcohol-related problems could be prevented by quitting or limiting consumption of alcohol. We were interested in predicting alcohol-related problems using multiple linear regression and regression trees, and then comparing the regressions to the tree. Impaired control, anxiety sensitivity, mother permissiveness, father permissiveness, gender, and age were included as predictors. The data used was comprised of participants (n=835) sampled from students at Arizona State University. A multiple linear regression without interactions, multiple linear regression with two-way interactions and squares, and a regression tree were used and compared. The regression and the tree had similar results. Multiple interactions of variables predicted alcohol-related problems. Overall, the tree was easier to interpret than the regressions, however, the regressions provided specific predicted alcohol-related problems scores, whereas the tree formed large groups and had a predicted alcohol-related problems score for each group. Nevertheless, the tree still predicted alcohol-related problems nearly as well, if not better than the regressions.
Date Created
2016-12
Agent