Social networking platforms have redefined communication, serving as conduits forswift global information dissemination on contemporary topics and trends. This research probes information cascade (IC) dynamics, focusing on viral IC, where user-shared information gains rapid, widespread attention. Implications of IC span advertising, persuasion, opinion-shaping, and crisis response. First, this dissertation aims to unravel the context behind viral content, particularly in the realm of the digital world, introducing a semi-supervised taxonomy induction framework (STIF). STIF employs state-of-the-art term representation, topical phrase detection, and clustering to organize terms into a two-level topic taxonomy. Social scientists then assess the topic clusters for coherence and completeness. STIF proves effective, significantly reducing human coding efforts (up to 74%) while accurately inducing taxonomies and term-to-topic mappings due to the high purity of its topics. Second, to profile the drivers of virality, this study investigates messaging strategies influencing message virality. Three content-based hypotheses are formulated and tested, demonstrating that incorporation of “negativity bias,” “causal arguments,” and “threats to personal or societal core values” - singularly and jointly - significantly enhances message virality on social media, quantified by retweet counts. Furthermore, the study highlights framing narratives’ pivotal role in shaping discourse, particularly in adversarial campaigns. An innovative pipeline for automatic framing detection is introduced, and tested on a collection of texts on the Russia-Ukraine conflict. Integrating representation learning, overlapping graph-clustering, and a unique Topic Actor Graph (TAG) synthesis method, the study achieves remarkable framing detection accuracy. The developed scoring mechanism maps sentences to automatically detect framing signatures. This pipeline attains an impressive F1 score of 92% and a 95% weighted accuracy for framing detection on a real-world dataset. In essence, this dissertation focuses on the multidimensional exploration of information cascade, uncovering the context and drivers of content virality, and automating framing detection. Through innovative methodologies like STIF, messaging strategy analysis, and TAG Frames, the research contributes valuable insights into the mechanics of viral content spread and framing nuances within the digital landscape, enriching fields such as advertisement, communication, public discourse, and crisis response strategies.