Our ability to understand networks is important to many applications, from the analysis and modeling of biological networks to analyzing social networks. Unveiling network dynamics allows us to make predictions and decisions. Moreover, network dynamics models have inspired new ideas for computational methods involving multi-agent cooperation, offering effective solutions for optimization tasks. This dissertation presents new theoretical results on network inference and multi-agent optimization, split into two parts -

The first part deals with modeling and identification of network dynamics. I study two types of network dynamics arising from social and gene networks. Based on the network dynamics, the proposed network identification method works like a `network RADAR', meaning that interaction strengths between agents are inferred by injecting `signal' into the network and observing the resultant reverberation. In social networks, this is accomplished by stubborn agents whose opinions do not change throughout a discussion. In gene networks, genes are suppressed to create desired perturbations. The steady-states under these perturbations are characterized. In contrast to the common assumption of full rank input, I take a laxer assumption where low-rank input is used, to better model the empirical network data. Importantly, a network is proven to be identifiable from low rank data of rank that grows proportional to the network's sparsity. The proposed method is applied to synthetic and empirical data, and is shown to offer superior performance compared to prior work. The second part is concerned with algorithms on networks. I develop three consensus-based algorithms for multi-agent optimization. The first method is a decentralized Frank-Wolfe (DeFW) algorithm. The main advantage of DeFW lies on its projection-free nature, where we can replace the costly projection step in traditional algorithms by a low-cost linear optimization step. I prove the convergence rates of DeFW for convex and non-convex problems. I also develop two consensus-based alternating optimization algorithms --- one for least square problems and one for non-convex problems. These algorithms exploit the problem structure for faster convergence and their efficacy is demonstrated by numerical simulations.

I conclude this dissertation by describing future research directions.