Postpartum depression is recognized as the most common psychiatric disorder that appears in approximately 10-15% of women, with higher frequencies among low-income minority women. Past studies have revealed that depressive symptoms negatively impact child development and mother-child synchrony. The current study's purpose was to explore the effects of postpartum depressive symptoms on later dyadic dysregulation. The data was collected from Las Madres Nuevas' study, a longitudinal investigation. Participants were 322 Mexican and Mexican American mother-infant dyads from the Phoenix metropolitan area who were recruited though a Maricopa Integrated Health System (MIHS) prenatal clinic. The Edinburgh Postnatal Depression Scale (EPDS) was used to measure depression 6 weeks postpartum. Additionally, the dysregulation-coding scheme used at child's 24 months of age measured the children's, mothers', and dyads' regulatory skills throughout their interactions with each other. Linear regression analyses were the central analyses of this study. In the first regression analysis, results showed that mother's age at prenatal visit (p= 0.44), 6-week depression score (p= 0.37), mother's education (p= 0.77), and number of biological children (p= 0.28) did not significantly predict dyadic dysregulation at 24 months. The second linear regression analysis concluded that the 6-week depression score, mother's country of birth, the interaction of maternal depression and country of birth, mother's education, mother's age at prenatal visit, and number of biological children also did not predict dyadic dysregulation at 24 months. Although not statistically significant, the findings suggest that the Hispanic Paradox theory, conservation of native cultural values, and strong social support have protective effects in Mexican immigrant and Mexican American childbearing women.