Inflammatory genes are known to only show in African Americans and non-Hispanic Whites. The objective of this study was to observe the correlation from the obtained data of the prevalence of the APOE ε4 genotype. We examined cerebral free-water, a marker of neuroinflammation, hippocampal volume, and volume of white-matter hyperintensities in African Americans (AA) and non-Hispanic Whites who were categorized in groups based on whether they had APOE ε4 allele or not. AA had lower prevalence of APOE e4 genotype than non-Hispanic Whites. AA groups have a slightly higher hippocampal volume compared to the Non-Hispanic White (NHW) groups. African Americans also reported increased white-matter hyperintensities and cerebral free-water. Hippocampal atrophy is associated with Alzheimer's disease, this might suggest that the AA groups have a lower risk of Alzheimer's, although further research is needed to confirm this relationship. Lastly, our findings also suggest other potential socioeconomic factors that could contribute to increased incidence of dementia among AA and potential resilience factors early in the course of Alzheimer’s disease process.

Patients receiving total knee arthroplasty surgery received either IV Meloxicam or Oral Celecoxib based on the hospital where they were treated. Otherwise, the operation and post-surgical pain protocol were kept as identical as possible. Surveys were administered at 24, 48, and 72 hours after surgery where patients reported their current pain level, and cumulative number or narcotic pain pills taken since surgery. Results showed a trend at each measured time interval for those receiving IV Meloxicam to report lower pain scores and less narcotic usage on average. Only the pain score difference reported at 72 hours was statistically significant. Due to limited number of study participants, further testing would be needed to determine if other observed differences would become statistically significant.