Wire connected solar cells are a promising new technology that can increase the efficiency and reduce the cost of solar modules. The use of wire rather than ribbon bus bars can lead to reduced shading, better light trapping, and reduced material costs, all while eliminating the need for soldering. This research first analyzes the optimal wire gauge to reduce cracking and improve efficiency. Wire sizes between 20 AWG and 28 AWG were tested, with the optimal size being between 24 AWG and 26 AWG for the ethylene vinyl acetate (EVA) layer used in the module. A polyethylene sheet was then added between the wires and EVA layer to prevent the EVA from running underneath the wires during lamination, ultimately allowing for a more uniform contact and only a slight reduction in quantum efficiency. Then, a comparison between tinned copper wires and indium coated copper wires is shown. A mini-module efficiency of 20.0% has been achieved using tinned copper wires, while indium coated copper wires have produced a mini-module efficiency of 21.2%. Thus, tinned copper wires can be a viable alternative to indium coated copper wires, depending on the needs of the customers and the current price of indium. The module design throughout the research utilizes a planar assembly method, which improves the ease of manufacturing for wire interconnection technology. A two-cell base component is constructed and shown, with the intended future application of making large wire connected modules. Finally, wire applications in both single-cell and four-cell flexible modules are explored, with an efficiency of 18.65% achieved on a single-cell, flexible, heterojunction solar module using wire interconnections. A fully flexible four-cell string is developed, and future recommendations for related research are included.