Phishing is one of most common and effective attack vectors in modern cybercrime. Rather than targeting a technical vulnerability in a computer system, phishing attacks target human behavioral or emotional tendencies through manipulative emails, text messages, or phone calls. Through PyAntiPhish, I attempt to create my own version of an anti-phishing solution, through a series of experiments testing different machine learning classifiers and URL features. With an end-goal implementation as a Chromium browser extension utilizing Python-based machine learning classifiers (those available via the scikit-learn library), my project uses a combination of Python, TypeScript, Node.js, as well as AWS Lambda and API Gateway to act as a solution capable of blocking phishing attacks from the web browser.