A Cross-Sectional Analysis on Cannabis- and Alcohol-Related Psychosis Visits in Arizona State Hospitals from 2016-2022

Objective: This study examined time trends in associations of cannabis- and alcohol-related hospital visits with psychosis-related hospital visits in Arizona from 2016 to 2022. Methods: Data were emergency department and inpatient hospital visits from all hospitals licensed and regulated by the Arizona Department of Health Services from January 2016 to December 2022 (n=21,921,214 visits). For each visit, data included patient demographics and International Classification of Diseases, 10th Revision, Clinical Modification (ICD-10-CM) codes in up to 25 diagnostic fields. Exposures were cannabis and alcohol-related diagnoses (use, abuse, dependence), and the outcome was psychosis diagnoses. Results: In any given year from 2016 to 2022, emergency department and inpatient hospital visits involving a cannabis-related diagnosis were 6-7 times more likely also to receive a psychosis diagnosis when compared with visits that did not include a cannabis-related diagnosis. By comparison, emergency department and inpatient hospital visits involving an alcohol-related diagnosis were only three times more likely also to receive a psychosis diagnosis.