Description
Anelloviruses are small, negative-sense, single-stranded DNA viruses that have are found to be present in over 90% of adult humans. Despite being highly prevalent, little is known about the biology or pathogenic potentials of the anelloviruses. Initially, the family Anelloviridae, contained 14 genera. However, in the last few years, there have been an abundant number of diverse anelloviruses that were identified in various organisms. Thus, a new criterion for anelloviruses classification was necessary to establish new genera and species to accommodate unclassified anelloviruses. As part of an ongoing effort to characterize the human virome of female genital tract (FGT), we performed virome metagenomic sequencing of Peruvian women living with HIV, and we have identified 7 novel anellovirus genome sequences found in cervicovaginal clinical specimens. Through phylogenetic and sequence analyses of the new characterization criteria, we classified the genome sequences as three novel anellovirus genera, provisionally named, Petorquevirus, Sadetorquevirus, and Quoptorquevirus.
Details
Title
- Characterization of Mammalian Anelloviruses in Clinical Samples
Contributors
- Do, Eric (Author)
- Lim, Efrem (Thesis director)
- Kaelin, Emily (Committee member)
- Barrett, The Honors College (Contributor)
- Economics Program in CLAS (Contributor)
- School of Molecular Sciences (Contributor)
- School of Life Sciences (Contributor)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2024-05
Resource Type
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