Using Salmonella as an Anti-Cancer Platform through the Regulation of Flagellin’s Cellular Concentration

Cancer is a disease that occurs when the cells in the body grow and replicate uncontrollably while spreading throughout the body. Apart from the pre-existing treatments, bacteria based treatments maybe used as an alternative. The main system used to deliver antigens to host tissues was Salmonella. In order to use Salmonella as an anti-cancer platform, there are three major steps which must be followed: cell lysis, tumor navigation, and Salmonella tumor persistence.