With an ever-increasing diagnosis rate and no universal cure, eosinophilic esophagitis (EoE) lacks conclusive data regarding the onset of its autoimmune response and its preferred relation to assigned sex males. This thesis seeks to analyze the effects that assigned sex and determinants of health have on EoE diagnosis through previous research and survey development. Upon constructing a Qualtrics survey to collect data patterns and trends of subjects diagnosed with this autoimmune disorder, COVID-19 created a halt in its distribution and data collection. This unexpected event led to the collection and compilation of pre-existing research to be implemented into this thesis as a substitute. The key results of this thesis revealed that in twenty research studies regarding sex differences in EoE, at least 70% of patients diagnosed with EoE were male (Liacouras, 2005). With inconclusive results as to why males are diagnosed at a higher rate, results have not confirmed if this percentage ratio is due to social or genetic factors. To conclude, males are predominately diagnosed with EoE in comparison to the female and intersex population, however, with no data currently available on the effects that EoE has on intersex humans, it cannot be determined what factors create this recurring pattern.

This project covers the history, function, and issues with campus policing in general across the United States and specifically at Arizona State University. With campus policing overall, this project discusses the issues of power and issues of race, racial profiling, and racism. With the Arizona State University police department, this project discusses the issues of how sexual assault has been handled, issues of transparency, lack of screening/qualifications/training, and issues of race, racial profiling, and racism. All of these issues are studied using specific cases and instances. Several suggestions for improvement are then covered, including the removal of police presence on campus, improved training, and increased accountability and transparency measures.

This project seeks to probe into an unexplored horizon of young adult literature studies: the empowering potential of Young Adult Fantasy (YAF) with queer Latinx representation for queer Latinx youth. The two theoretical frameworks of analysis used in this project are: Dr. Rudine Sims Bishop’s concept of “Mirrors, Windows, and Sliding Glass Doors” (1990) and Gloria E. Anzaldúa’s “Conocimiento” individuation journey.

This project was designed to assess whether Arizona State University’s current Health and Counseling services perpetuate healthcare discrimination against its LGBTQIA+ student population: a pervasive problem that both researchers and patients have observed in the general healthcare landscape--on university campuses and beyond. A two-part online survey, including multiple-choice and free-response questions, was administered to ASU students attending any of the four campuses in order to receive a wide range of student feedback from diverse populations and assess the queer and transgender healthcare experience on campus. This survey data was used to pinpoint gaps and/or problems in student care and to assess how these concerns might be addressed. Results showed that a number of participants experienced discrimination, including incorrect references to gender pronouns, name preferences, and sexual identity. In response to survey participants’ desire for clearer information about health care services, a prototype for a resource pamphlet and corresponding mock-up of an online platform were created. These prototype resources clearly outline information about the sexual, mental, and physical health resources provided by ASU and include supplementary off-campus programs to fill the gaps in university services. Additionally, these findings were used to create a prototype that could be used to help ensure healthcare workers are familiar with LGBTQIA+ specific healthcare needs.

The goal of this thesis was to simplify the sample preparation process for cryogenic electron microscopy (cryo-EM), clearing the way for the imaging of larger biomolecules and further expansion of the field. Various protic ionic liquids (PILs) were chosen for synthesis according to their pH and other physical properties. After several failed synthesizes, one PIL, cholinium dihydrogen phosphate, was chosen for further testing. This solution was put through a series of vitrification tests in order to understand its crystallization limits. Once limits were understood, cholinium dihydrogen phosphate was combined with ribosomal proteins and viewed under a transmission electron microscope to collect negative stain images. After adjusting the ratio of PIL to buffer and the concentration of ribosomes, images of whole intact ribosomes were captured. Samples were then placed in an EM grid, manually dipped in liquid nitrogen, and viewed using the the cryo-EM. These grids revealed ice too thick to properly image, an issue that was not solved by using a more aggressive blotting technique. Although the sample preparation process was not simplified, progress was made towards doing so and further testing using different techniques may result in success.

There are issues at the Arizona State University Tempe campus with the culture of food and many of these issues stem from the dining halls. To determine the extent of this problem, our group conducted research on the Tempe campus through student surveys and in person discussions. What we found were limitations in both the healthy options and hours of operations at the dining halls. Students also showed general dissatisfaction with their diets. Our solution is the Devil Crate, a subscription box that conveniently delivers healthy food along with a personal touch. The recipes, health information and tips inside the subscription box are given to motivate students to eat healthy. We also realized that this solution could potentially solve another issue facing our community, which is food waste. The sustainably sourced food allows the price of Devil Crate to be lowered while eliminating the waste of produce. Once this solution was formulated, a test trial was conducted to measure the demand for such a product among students. The Devil Crate was produced, sold, and delivered to 2 students, both of whom were pleased and willing to recommend Devil Crate to others. The end goal is to incorporate Devil Crate into the meal plans to offer more options in this limited food environment and promote healthy eating among students.

Human trafficking is a widespread global health issue impacting communities both locally and globally. Despite its prevalence in our world, there is a lack of education amongst healthcare providers. Research suggests that more than 80 percent of human trafficking victims encountered one or more healthcare professionals while being trafficked. Of these providers encountered, 60 percent were emergency department personnel (Lederer & Wetzel, 2014). Although emergency department personnel have a high rate in interaction with victims, less than 5 percent have received formal training regarding human trafficking (Lederer & Wetzel, 2014). It is my goal to better educate current and future healthcare professionals on human trafficking. Through education, more victims can be recognized and be offered the resources they deserve. In order to do this, I want to understand current perceptions, knowledge, and beliefs that healthcare personnel have, and how education affects these perceptions. To gain this information, I will distribute the same survey to healthcare professionals before and after receiving a formal training on human trafficking. Through this survey, I hope to better understand how education affects people’s perceptions, knowledge, and beliefs on human trafficking.

Thousands of human lives are lost every day due to chronic diseases, some more preventable than others. For years, the gold standard for diagnosing and monitoring these diseases has been through traditional methods such as individualized doctor-patient clinical evaluations, usually involving laboratory tests. These methods, though effective, can be costly, time-consuming, and fail to encompass an overarching perspective of the health profile of the larger population. Wastewater-based epidemiology (WBE) has successfully been employed for decades as a population-level data source informing on the consumption of licit and illicit substance use. It also is showing promise for its use as a community-wide diagnostic tool for broader public health measurements. This literature review constitutes a theoretical evaluation of the potential use of WBE for monitoring the top two deadly diseases in the United States; cardiovascular disease (CVD) and cancer. Literature-reported metabolites indicative of these diseases were evaluated to determine if they were capable of being identified and monitored in wastewater. Potential analytes include cardiac-specific troponin, α-fenotroin, and inositol. Results obtained within suggest WBE could be used as a viable and economical tool to track and monitor the top deadly diseases in human populations. This methodology could be implemented in tandem with current practices in order to provide a more holistic understanding of prevalence and risk for CVD and cancer.

We live in an era where the notion of feminism is widespread. Just walking on the Arizona State University campus, one can see people wearing t-shirts and holding coffee cups that say "FEMINIST," working from computers covered in stickers calling for gender equity. I, myself, am a feminist. On any given day, I fit in perfectly with many others on campus - sporting a t-shirt that says, "Raise Boys and Girls the Same Way," and lugging around my laptop covered in feminist propaganda stickers. I subscribe to Chimamanda Ngozi Adichie's definition of feminism. In essence, a feminist is "a person who believes in the social, political, and economic equality of the sexes," regardless of religion, ethnicity, race, and class (Adichie, 2012). Through the lens of this definition and those like it, women have made many advancements (though there is still significant progress to be made in this arena, particularly for women of color) – more women participate in the workforce and education, women have gained greater autonomy over their bodies, and domestic responsibilities are, in many societies, no longer only assumed by women.

The United States has been facing a resurgence of vaccine preventable infectious diseases. Non-medical vaccination exemptions (NMEs) which include religious exemptions and philosophical vaccine exemptions are contributing factors in state vaccination rates dropping. The policies surrounding such exemptions vary from state to state. Some states with higher rates of nonmedical vaccine exemptions are dealing with repercussions for this including vaccination rates falling below desired herd immunity and thus putting vulnerable populations such as those who are immunocompromised, too young for vaccination and the elderly at a higher risk.

This thesis aims to examine vaccine preventable re-emerging infectious diseases in the United States with the objective of reaching vaccine hesitant populations and providing them with the tools to make informed decisions to seek out immunizations. This will be done by exploring five different diseases and infections, discussing why some individuals feel hesitant to get immunizations, examining how nonmedical vaccine exemptions are correlated to increased cases of disease outbreaks, looking into state laws specifically focused on countering nonmedical vaccine exemptions and the steps that can be taken moving forward.