Universal Basic Income is a proposed policy where the government would regularly pay all citizens in cash. The idea of a Universal Basic Income (UBI) has had a resurgence in recent years because of popular figures like Andrew Yang and Elon Musk, but its history and potential implications go deep into the structure of human society. This thesis delves into how a basic income would transform social concepts of work and disrupt the personal economic model. With the bargaining power and freedom granted by a basic income, workers would find themselves in a position of work freedom and choice that has never existed in human history. With new freedom to do as they wish, the place of work in people’s lives needs to be reimagined as a source of fulfillment instead of an unlikeable but necessary part of everyday life. Workers will be given the choice to leave unfair or unfulfilling work and decide for themselves how they want to contribute within society. From increasing mental and economic well-being for most Americans to serving as a response to unemployment trends in the automated future, to encouraging greater business innovation, there are myriad ways in which basic incomes have the potential to benefit society. Framed by Martin Luther King Jr. and Franklin Delano Roosevelt as the only policy capable of abolishing poverty forever, Universal Basic income will be an important feature of transformative innovative policy advocacy until it is adopted by a major world government at which point the effects in practice will become clear.

Appearance ideals are standards of beauty imposed by a culture or society, that are unrealistic and impossible to achieve. Research documents the existence of three appearance ideals, thin, muscular and hourglass ideals. The thin ideal is the pursuit of a very thin and low body weight. The muscular ideal is the pursuit of a toned and fit body. The hourglass ideal is the pursuit of a shapely body with bigger breasts and hips/buttocks than waist. These ideals are associated with disordered eating. However, no current study has examined the prevalence of all three ideals, or how the combination of ideals relates to dietary restraint, one example of a disordered eating behavior. This study was conducted on 505 undergraduate women at Arizona State University, who were completing research credit for a psychology course. The women participated in an online survey that assessed their demographics, each ideal, and dietary restraint. Results show that all combinations of ideals exist. Specifically, 41.5% of the sample endorse high levels of all three ideals, while 12.5% report thin and muscular ideals, 9.5% report thin and hourglass ideals, 9.9% report hourglass and muscular ideals, 8.4% report low levels of all three ideals, 6.4% report muscular ideal only, 6.4% report hourglass ideal only, and 5.6% report thin ideal only. Endorsing more than one ideal significantly associated with dietary restraint. Findings fulfill an important gap in the literature, suggest future directions for research, and have important clinical implications.

This thesis responds to the question, "Can Science Make Sense of Life?" through a structural lens of the Human Germline Genetic Editing debate. I explore who is absent from the table, and how the ways of thinking that dominate marginalize and exclude alternative frameworks and considerations. This analysis is centered around an examination of several perspectives from the disability community and an in-depth study of how the Orthodox Jewish community contends with genetic disease. These perspectives illuminate several lessons that prove to bring insight not merely to questions of permissibility on genetic editing, but also offer reflections on the larger relationship between science, technology, and society. I then return to the mainstream genetic editing debate to show how the culture it is born out of and the structures it has ingrained prevent lessons such as these from impacting the conversation. In light of such structures that continuously reproduce the assertion that it is science, not humanity, that is able to make sense of life, my final argument is that though science tends to gatekeep questions of emerging technologies by centering conversations on highly advanced and methodological considerations, public individuals need not feel as if they are irrelevant or unessential. Though science may offer one solution, it is the individuals and communities, not results from a lab, that are equipped to determine if it is the best solution.

Edge computing is a new and growing market that Company X has an opportunity to expand their presence. Within this paper, we compare many external research studies to better quantify the Total Addressable Market of the Edge Computing space. Furthermore, we highlight which Segments within Edge Computing have the most opportunities for growth, along with identify a specific market strategy that Company X could do to capture market share within the most opportunistic segment.

In the preface to On War, Clausewitz describes his work as a series of loosely connected pure nuggets of knowledge. He then states his hope that his nuggets would eventually be connected and consolidated into what he calls a “final casting without dross”. It is the goal of this work to begin that consolidation and take steps towards a final casting and a more comprehensive understanding of war, combining Clausewitz’s models with modern findings not available at the time of On War’s conception. Using Clausewitz’s combat equation as a foundation for a framework on the nature of war, this work will synthesize many of On War’s central concepts, while also expanding upon the terms and mechanics presented in Book One. It is hoped that the resulting model will combine the best of Clausewitz’s findings in a way that makes the sum of the parts greater than the whole, and allows previous findings which were isolated to a particular silo of study to be cross examined for exponential application to the study of war. This may in due time, with additional contributions, result in the ever desired revolution in military affairs and enhance the military sciences for years to come.

This thesis research aims to define, identify, and promote community theatre as a “third space” for disadvantaged youth. A third space is defined by the Oxford dictionary as “...the in-between, or hybrid, spaces, where the first and second spaces work together to generate a new third space. First and second spaces are two different, and possibly conflicting, spatial groupings where people interact physically and socially: such as home (everyday knowledge) and school (academic knowledge)” (Oxford Dictionary, 2021). For disadvantaged youth, the creation of a third space in the theatre can give them a safe environment away from issues they may have at home or at school, it can further their learning about themselves and others, and it can also help those youth feel a sense of belonging to a community larger than themselves. Because of these benefits, it is clear that performing arts programs can offer a great impact on disadvantaged youth; however, many theatre companies struggle to market their programming to said communities. This may be in part, due to low marketing budgets, no specificity in labor resources dedicated to youth programming, or ineffective marketing strategies and tactics.<br/>In order to ideate marketing recommendations for these organizations, primary research was conducted to determine the attitudes and beliefs revolving around youth participation in community theatre, as well as the current marketing strategies and tactics being utilized by programmers. Participants included program managers of youth theatre programs, as well as youth participants from several major cities in the U. S. The secondary research aims to better understand the target demographic (disadvantaged youth), the benefits derived from participation in arts programming, and marketing strategies for the performing arts. Following data analysis are several recommendations for the learning, planning, and implementation of marketing strategies for theatre programmers.

Veterans are approximately 30% more likely than non-veterans to suffer from severe hearing impairment. Tinnitus, or ringing in the ears, which is increasingly common among military service men and women, has been linked to significant cognitive and psychological impairment and can be worsened by the same sounds that trigger post-traumatic stress disorder (PTSD). In fact, tinnitus and PTSD often present as comorbidities, and recent studies suggest these two disorders may share a common neurological pathway. Additional studies are required to better understand the connection between hearing loss and impaired cognitive function such as that observed in with PTSD. Here, we use the fruit fly, Drosophila melanogaster, to explore the relationship between hearing loss and cognitive function. Negative geotaxis climbing assays and courtship behavior analysis were used to examine neurobehavioral changes induced by prolonged, intense auditory stimulation. Preliminary results suggest that exposure to loud noise for an extended period of time significantly affected Drosophila behavior, with males being more sensitive than females. Based on our results, there appears to be a potential connection between noise exposure and behavior, further suggesting that Drosophila could be an effective model to study the link between hearing loss and PTSD.

Background: The purpose of this study was to assess the efficacy of a lifestyle intervention on cardiorespiratory fitness in Latino youth with obesity and prediabetes. <br/>Methods: Participants (n=50) in this study were taken from a larger randomized controlled trial (n=180, BMI ≥ 95th percentile). Youth participated in a 6-month lifestyle intervention that included physical activity (60 minutes, 3x/week) and nutrition and wellness classes (60 minutes, 1x/week) delivered to families at the Lincoln Family YMCA in Downtown Phoenix. The primary outcome was cardiorespiratory fitness measured at baseline and post-intervention.<br/>Results: The mean BMI for the sample was 33.17 ± 4.54 kg/m2, which put the participants in the 98.4th percentile. At baseline, the mean VO2max was 2737.02 ± 488.89 mL/min. The mean relative VO2max was 30.65 ± 3.87 mL/kg/min. VO2max values significantly increased from baseline to post-intervention (2737.022 ± 483.977 mL/min vs 2932.654 ± 96.062 mL/min, p<0.001). <br/>Conclusion: Culturally-grounded, family-focused lifestyle interventions are a promising approach for improving cardiorespiratory fitness in high-risk youth at risk for diabetes.

This thesis includes three separate documents: a) a comprehensive document detailing the methods and analysis of the creative factors tied to series success, b) an hour long pilot script based on this data, and c) an industry-standard pitch deck for a TV show created with data insights. In a larger sense, the aim of this study is to take the first steps in remedying information asymmetry between streaming services and content creators. If streaming services were more transparent with their data and communicated to their creators what has been proven to work in the past, showrunners and staff writers could have a new tool to increase the competitiveness of their series and aid in show renewal each year.

Mutations in the DNA of somatic cells, resulting from inaccuracies in DNA<br/>replication or exposure to harsh conditions (ionizing radiation, carcinogens), may be<br/>loss-of-function mutations, and the compounding of these mutations can lead to cancer.<br/>Such mutations can come in the form of thymine dimers, N-𝛽 glycosyl bond hydrolysis,<br/>oxidation by hydrogen peroxide or other radicals, and deamination of cytosine to uracil.<br/>However, many cells possess the machinery to counteract the deleterious effects of<br/>such mutations. While eukaryotic DNA repair enzymes decrease the incidence of<br/>mutations from 1 mistake per 10^7 nucleotides to 1 mistake per 10^9 nucleotides, these<br/>mutations, however sparse, are problematic. Of particular interest is a mutation in which<br/>uracil is incorporated into DNA, either by spontaneous deamination of cysteine or<br/>misincorporation. Such mutations occur about one in every 107 cytidine residues in 24<br/>hours. DNA uracil glycosylase (UDG) recognizes these mutations and cleaves the<br/>glycosidic bond, creating an abasic site. However, the rate of this form of DNA repair<br/>varies, depending on the nucleotides that surround the uracil. Most enzyme-DNA<br/>interactions depend on the sequence of DNA (which may change the duplex twist),<br/>even if they only bind to the sugar-phosphate backbone. In the mechanism of uracil<br/>excision, UDG flips the uracil out of the DNA double helix, and this step may be<br/>impaired by base pairs that neighbor the uracil. The deformability of certain regions of<br/>DNA may facilitate this step in the mechanism, causing these regions to be less<br/>mutable. In DNA, base stacking, a form of van der Waals forces between the aromatic<br/>nucleic bases, may make these uracil inclusions more difficult to excise. These regions,<br/>stabilized by base stacking interactions, may be less susceptible to repair by<br/>glycosylases such as UDG, and thus, more prone to mutation.