Matching Items (43,917)
Description
Building mathematical models and examining the compatibility of their theoretical predictions with empirical data are important for our understanding of evolution. The rapidly increasing amounts of genomic data on polymorphisms greatly motivate evolutionary biologists to find targets of positive selection. Although intensive mathematical and statistical studies for characterizing signatures of positive selection have been conducted to identify targets of positive selection, relatively little is known about the effects of other evolutionary forces on signatures of positive selection. In this dissertation, I investigate the effects of various evolutionary factors, including purifying selection and population demography, on signatures of positive selection. Specifically, the effects on two highly used methods for detecting positive selection, one by Wright's Fst and its analogues and the other by footprints of genetic hitchhiking, are investigated. In Chapters 2 and 3, the effect of purifying selection on Fst is studied. The results show that purifying selection intensity greatly affects Fst by modulating allele frequencies across populations. The footprints of genetic hitchhiking in a geographically structured population are studied in Chapter 4. The results demonstrate that footprints of genetic hitchhiking are significantly influenced by geographic structure, which may help scientists to infer the origin and spread of the beneficial allele. In Chapter 5, the stochastic dynamics of a hitchhiking allele are studied using the diffusion process of genetic hitchhiking conditioned on the fixation of the beneficial allele. Explicit formulae for the conditioned two-locus diffusion process of genetic hitchhiking are derived and stochastic aspects of genetic hitchhiking are investigated. The results in this dissertation show that it is essential to model the interaction of neutral and selective forces for correct identification of the targets of positive selection.
Contributors
Maruki, Takahiro (Author) / Kim, Yuseob (Thesis advisor) / Taylor, Jesse E (Thesis advisor) / Greenwood, Priscilla E (Committee member) / Hedrick, Philip W (Committee member) / Rosenberg, Michael S. (Committee member) / Arizona State University (Publisher)
Created
2011
Description
The purpose of this project was to examine the lives and solo piano works of four members of the early generation of female composers in Taiwan. These four women were born between 1950 and 1960, began to appear on the Taiwanese musical scene after 1980, and were still active as composers at the time of this study. They include Fan-Ling Su (b. 1955), Hwei-Lee Chang (b. 1956), Shyh-Ji Pan-Chew (b. 1957), and Kwang-I Ying (b. 1960). Detailed biographical information on the four composers is presented and discussed. In addition, the musical form and features of all solo piano works at all levels by the four composers are analyzed, and the musical characteristics of each composer's work are discussed. The biography of a fifth composer, Wei-Ho Dai (b. 1950), is also discussed but is placed in the Appendices because her piano music could not be located. This research paper is presented in six chapters: (1) Prologue; the life and music of (2) Fan-Ling Su, (3) Hwei-Lee Chang, (4) Shyh-Ji Pan-Chew, and (5) Kwang-I Ying; and (6) Conclusion. The Prologue provides an overview of the development of Western classical music in Taiwan, a review of extant literature on the selected composers and their music, and the development of piano music in Taiwan. The Conclusion is comprised of comparisons of the four composers' music, including their personal interests and preferences as exhibited in their music. For example, all of the composers have used atonality in their music. Two of the composers, Fan-Ling Su and Kwang-I Ying, openly apply Chinese elements in their piano works, while Hwei-Lee Chang tries to avoid direct use of the Chinese pentatonic scale. The piano works of Hwei-Lee Chang and Shyh-Ji Pan-Chew are chromatic and atonal, and show an economical usage of material. Biographical information on Wei-Ho Dai and an overview of Taiwanese history are presented in the Appendices.
Contributors
Wang, Jinding (Author) / Pagano, Caio (Thesis advisor) / Campbell, Andrew (Committee member) / Humphreys, Jere T. (Committee member) / Meyer-Thompson, Janice (Committee member) / Norton, Kay (Committee member) / Arizona State University (Publisher)
Created
2011
Description
Voltage Control Oscillator (VCO) is one of the most critical blocks in Phase Lock Loops (PLLs). LC-tank VCOs have a superior phase noise performance, however they require bulky passive resonators and often calibration architectures to overcome their limited tuning range. Ring oscillator (RO) based VCOs are attractive for digital technology applications owing to their ease of integration, small die area and scalability in deep submicron processes. However, due to their supply sensitivity and poor phase noise performance, they have limited use in applications demanding low phase noise floor, such as wireless or optical transceivers. Particularly, out-of-band phase noise of RO-based PLLs is dominated by RO performance, which cannot be suppressed by the loop gain, impairing RF receiver's sensitivity or BER of optical clock-data recovery circuits. Wide loop bandwidth PLLs can overcome RO noise penalty, however, they suffer from increased in-band noise due to reference clock, phase-detector and charge-pump. The RO phase noise is determined by the noise coming from active devices, supply, ground and substrate. The authors adopt an auxiliary circuit with inverse delay sensitivity to supply noise, which compensates for the delay variation of inverter cells. Feed-forward noise-cancelling architecture that improves phase noise characteristic of RO based PLLs is presented. The proposed circuit dynamically attenuates RO phase noise contribution outside the PLL bandwidth, or in a preferred band. The implemented noise-cancelling loop potentially enables application of RO based PLL for demanding frequency synthesizers applications, such as optical links or high-speed serial I/Os.
Contributors
Min, Seungkee (Author) / Kiaei, Sayfe (Thesis advisor) / Bakkaloglu, Bertan (Committee member) / Ozev, Sule (Committee member) / Towe, Bruce (Committee member) / Arizona State University (Publisher)
Created
2011
Description
ABSTRACT Group III-nitride semiconductor materials have been commercially used in fabrication of light-emitting diodes (LEDs) and laser diodes (LDs) covering the spectral range from UV to visible and infrared, and exhibit unique properties suitable for modern optoelectronic applications. Great advances have recently happened in the research and development in high-power and high-efficiency blue-green-white LEDs, blue LDs and other optoelectronic applications. However, there are still many unsolved challenges with these materials. In this dissertation, several issues concerning structural, electronic and optical properties of III-nitrides have been investigated using a combination of transmission electron microscopy (TEM), electron holography (EH) and cathodoluminescence (CL) techniques. First, a trend of indium chemical inhomogeneity has been found as the indium composition increases for the InGaN epitaxial layers grown by hydride vapor phase epitaxy. Second, different mechanisms contributing to the strain relaxation have been studied for non-polar InGaN epitaxial layers grown on zinc oxide (ZnO) substrate. Third, various structural morphologies of non-polar InGaN epitaxial layers grown on free-standing GaN substrate have been investigated. Fourth, the effect of the growth temperature on the performance of GaN lattice-matched InAlN electron blocking layers has been studied. Finally, the electronic and optical properties of GaN nanowires containing a AlN/GaN superlattice structure have been investigated showing relatively small internal electric field and superlattice- and defect-related emissions along the nanowires.
Contributors
Sun, Kewei (Author) / Ponce, Fernando (Thesis advisor) / Smith, David (Committee member) / Treacy, Michael (Committee member) / Drucker, Jeffery (Committee member) / Schmidt, Kevin (Committee member) / Arizona State University (Publisher)
Created
2011
Description
This paper outlines the three research projects that I performed between 2009-present: Slow Movement Training (SMT) lab, Self-education Through Embodied Movement (STEM), and the Athletic Movement Program (AMP). It first evaluates the major issues that spawned each research project, and then provides a framework for understanding the shift in the student-centered physical and mental movement practices that I developed in response to the need for reform. The content will address the personal and professional paradigmatic shift that I experienced through the lens of a practitioner and educator. It will focus heavily on the transitions between each of the projects and finally the emergence of the Athletic Movement Program. The focal point becomes one of community needs, alternate resources and hybrid-online classroom support. The paper concludes with an overview and content comparison between the one-size-fits-all model used within public movement education and Athletic Movement Programs' strengths and challenges.
Contributors
Croitoru, Michael (Author) / Mitchell, John D. (Thesis advisor) / Fitzgerald, Mary (Committee member) / Coleman, Grisha (Committee member) / Arizona State University (Publisher)
Created
2011
Description
The current study was a benefit cost analysis that examined mental and behavioral health and prescription drug service use data of 347 participants (212 youth and 135 caregivers) from a bereavement intervention, the Family Bereavement Program (FBP).The preliminary goals of the current study were to compare the FBP intervention and the Literature Control (LC) groups at the six year follow-up on: (a) number of participants using mental/behavioral health services and prescription drugs, (b) the frequency of use of mental/behavioral health services and prescription drugs, and (c) the costs of mental/behavioral health services and prescription drugs. The final, and primary goal, was to (d) calculate the benefits of the FBP by analyzing the monetary difference between the LC and FBP groups in terms of cost of services used and then by applying those benefits to the cost of the intervention. Data representing participating youths' and caregivers' mental health service use and prescription drug use at the sixth year post-intervention were collected, as were the costs of those services. Results indicated that fewer FBP participants used services and prescription drugs than the Literature Control (LC) participants, but FBP participants, particularly the youth, used some low intensity services more frequently whereas the LC youth used more intensive and costly services more frequently. Consequently, service costs were greater for participants in the LC group than for participants in the FBP group. The benefit cost ratio revealed that the FBP, as delivered, saved society between $.15 and $.27 in mental and behavioral health costs for every dollar spent on the intervention. Implications of these findings and directions for future research are discussed.
Contributors
Porter, Michèle M (Author) / Hanish, Laura D. (Thesis advisor) / Sandler, Irwin N. (Committee member) / Wolchik, Sharlene A (Committee member) / Johnson, William G. (Committee member) / Arizona State University (Publisher)
Created
2011
Description
ABSTRACT The purpose of this study was to determine if a significant difference was found comparing posttest scores between students who took a career strategy course in a face-to-face (f2f) format (n=156) and students who took the same course in a new online format (n=64). A review of literature pertaining to online learning, career services on college campuses, and career classes was provided. Data was collected via an action research design utilizing an intervention of an online delivery format. A quasi-experimental design allowed descriptive data to be collected which was analyzed by use of independent-samples t-tests, comparison of means, and frequency analysis to gain data pertinent to the research question. Quantitative results in four areas: posttest scores, pretest scores, learning gain, and course evaluation data were provided. Pretest and subgroup analysis were also utilized to add richness to the data. Results found that the career strategy course delivered in an online delivery format resulted in no significant differences in posttest scores when compared to the f2f delivery method posttest scores. This result is in agreement with the literature in online learning delivery formats compared to f2f delivery formats. The results of this study showed evidence to support the continuation of new iterations of the online delivery method for the career strategy course used in the study. Implications of these findings were discussed for the researcher's local community of practice, the larger community of practice, collegiate career services, as well as possibilities for future experimentation in career services and strategic career courses with other online formats in the future.
Contributors
Burns, Kevin L (Author) / Ewing, Kris (Thesis advisor) / Rund, James (Committee member) / Mosco, Michele (Committee member) / Arizona State University (Publisher)
Created
2011
Description
The purpose of this study was to examine the longitudinal relations of maternal behaviors, children`s temperamental negative emotionality, and children`s emotion perception processes, including emotion perception accuracy (EPA) and emotion perception bias (EPB), to children`s conduct disorder symptoms in a normative sample. Separate structural equation models were conducted to assess whether parenting or children`s proneness to negative emotions at 24-30 (T2), 36-42 (T3) and 48-54 (T4) months predicted children`s EPA and EPB over time, and whether T3 and T4 children`s emotion perception processes were predictive of children`s conduct disorder at 72 months of age (T5). None of the hypothesized longitudinal relations was supported; however, other noteworthy results were observed. T3 children`s proneness to negative emotions was positively related to children`s concurrent bias toward anger. The latent constructs of negative parenting, children`s proneness to negative emotions, and the observed measure of children`s emotion perception accuracy showed stability over time, whereas the observed measures of children`s bias toward understanding distinct negative emotions were unrelated across time. In addition, children`s expressive language was predicted by children`s earlier emotion perception accuracy, which emphasized the importance of improving children`s emotion understanding skills during early years. Furthermore, the previously established negative relation between EPA and EPB variables was only partially supported. Findings regarding the relations between parenting, children`s negative emotionality and emotion perception processes are discussed from a developmental perspective.
Contributors
Seyed Nozadi, Sara (Author) / Spinrad, Tracy L. (Thesis advisor) / Eisenberg, Nancy (Committee member) / Bradley, Robert (Committee member) / Eggum, Natalie (Committee member) / Arizona State University (Publisher)
Created
2011
Description
Climate change has the potential to affect vegetation via changes in temperature and precipitation. In the semi-arid southwestern United States, heightened temperatures will likely lead to accelerated groundwater pumping to meet human needs, and altered storm patterns may lead to changes in flood regimes. All of these hydrologic changes have the potential to alter riparian vegetation. This research, consisting of two papers, examines relationships between hydrology and riparian vegetation along the Verde River in central Arizona, from applied and theoretical perspectives. One paper investigates how dominance of tree and shrub species and cover of certain functional groups change along hydrologic gradients. The other paper uses the Verde River flora along with that river's flood and moisture gradients to answer the question of whether functional groups can be defined universally. Drying of the Verde River would lead to a shift from cottonwood-willow streamside forest to more drought adapted desert willow or saltcedar, a decline in streamside marsh species, and decreased species richness. Effects drying will have on one dominant forest tree, velvet ash, is unclear. Increase in the frequency of large floods would potentially increase forest density and decrease average tree age and diameter. Correlations between functional traits of Verde River plants and hydrologic gradients are consistent with "leaf economics," or the axis of resource capture, use, and release, as the primary strategic trade-off for plants. This corresponds to the competitor-stress tolerator gradient in Grime's life history strategy theory. Plant height was also a strong indicator of hydrologic condition, though it is not clear from the literature if plant height is independent enough of leaf characteristics on a global scale to be considered a second axis. Though the ecohydrologic relationships are approached from different perspectives, the results of the two papers are consistent if interpreted together. The species that are currently dominant in the near-channel Verde River floodplain are tall, broad-leaf trees, and the species that are predicted to become more dominant in the case of the river drying are shorter trees or shrubs with smaller leaves. These results have implications for river and water management, as well as theoretical ecology.
Contributors
Hazelton, Andrea Florence (Author) / Stromberg, Juliet C. (Thesis advisor) / Schmeeckle, Mark W (Committee member) / Franklin, Janet (Committee member) / Arizona State University (Publisher)
Created
2011
Description
Two-dimensional vision-based measurement is an ideal choice for measuring small or fragile parts that could be damaged using conventional contact measurement methods. Two-dimensional vision-based measurement systems can be quite expensive putting the technology out of reach of inventors and others. The vision-based measurement tool design developed in this thesis is a low cost alternative that can be made for less than $500US from off-the-shelf parts and free software. The design is based on the USB microscope. The USB microscope was once considered a toy, similar to the telescopes and microscopes of the 17th century, but has recently started finding applications in industry, laboratories, and schools. In order to convert the USB microscope into a measurement tool, research in the following areas was necessary: currently available vision-based measurement systems, machine vision technologies, microscope design, photographic methods, digital imaging, illumination, edge detection, and computer aided drafting applications. The result of the research was a two-dimensional vision-based measurement system that is extremely versatile, easy to use, and, best of all, inexpensive.
Contributors
Graham, Linda L. (Author) / Biekert, Russell (Thesis advisor) / Macia, Narciso (Committee member) / Meitz, Robert (Committee member) / Arizona State University (Publisher)
Created
2011