In 2004, Amanda J. Drake and Brian R. Walker published “The Intergenerational Effects of Fetal Programming: Non-genomic Mechanisms for the Inheritance of Low Birth Weight and Cardiovascular Risk,” hereafter, “The Intergenerational Effects,” in the Journal of Endocrinology. In their article, the authors assert that cardiovascular disease may develop via fetal programming, which is when a certain event occurring during a critical point of pregnancy affects the fetus long after birth. Drake and Walker were among the first to show that the programming effects of cardiovascular disease could be sustained across generations through non-genetic means. In “The Intergenerational Effects,” the authors identify how non-genetic mechanisms may perpetuate fetal programming influences over generations, highlighting the importance for further research on fetal programming.
Details
- “The Intergenerational Effects of Fetal Programming: Non-genomic Mechanisms for the Inheritance of Low Birth Weight and Cardiovascular Risk” (2004), by Amanda J. Drake and Brian R. Walker
- Keller, Carrie (Author)
- Darby, Alexis (Editor)
- Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher)
- Arizona Board of Regents (Publisher)
- literature
- Reproductive Health
- Gestation
- Fetal Monitoring
- Fetal Distress
- Intrauterine Growth Retardation
- Fetal malnutrition
- Fetal behavior
- Fetal Programming
- Fetal Growth
- fetal development
- Embryonic and Fetal Development
- Embryo and Fetal Development
- Prenatal Programming
- Infant, Low Birth Weight
- Low Birth Weight
- Very Low Birth Weight
- Coronary Artery Disease
- Coronary heart disease
- Publications
- Reproduction
- Theories
- intergenerational effects
- pregnancy and genetic inheritance