Description
The source-sink model, first proposed by biologist Francis Crick in 1970, is a theoretical system for how morphogens distribute themselves across small fields of early embryonic cells. A morphogen is a substance that determines the fate and phenotype of a group of cells through a concentration gradient of itself across that group. Crick’s theory has been experimentally confirmed with several morphogens, most notably with the protein bicoid , the first discovered morphogen. The model provides a theoretical structure for the understanding of some features of early embryonic development.
Details
Title
- The Source-Sink Model
Contributors
- Resnik, Jack (Author)
- Wolter, Justin (Editor)
- Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. (Publisher)
- Arizona Board of Regents (Publisher)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2012-05-07
Subjects
Keywords
- Concept
- Theories
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