Full metadata
Title
Trends in Tissue-Specific Cancers
Description
A big part of understanding cancer is understanding the cellular environment itthrives in by analyzing it from a microecological perspective. Humans and other species
are affected by different cancer types, and this highlights the notion that there may be a
correlation between specific tissues and neoplasia prevalence. Research shows that
humans are the most susceptible to adenocarcinomas and carcinomas which include the
following tissues: lungs, breast, prostate, and pancreas. Furthermore, research shows that
adenocarcinoma accounts for 38.5% of all lung cancer cases, 20% of small cell
carcinomas, and 2.9% of large cell carcinoma. The incidence of the most common cancer
types in humans is consistently increasing annually. This study analyzes trends of tissue-specific cancers across species to examine possible contributors to vulnerability to
cancer. I predicted that adenocarcinomas would be the most prevalent cancer type across
the tree of life. To test this hypothesis, I reviewed over 130 species that reported equal to
or greater than 50 individual necropsy pathology records across 4 classes (Mammalia,
amphibia, Reptilia, Aves) and ranked them by neoplasia prevalence. This information was
then organized in tables in descending order. The study’s resulting tables and data
concluded that the hypothesis was correct. I found that across all species
adenocarcinomas were the most common cancer type and account for 30.4% of
malignancies reported among species. Future research should investigate how organ size
contributes to neoplasia prevalence.
Date Created
2022
Contributors
- PERAZA, ASHLEY (Author)
- Maley, Carlo (Thesis advisor)
- Boddy, Amy (Thesis advisor)
- Baciu, Cristina (Committee member)
- Arizona State University (Publisher)
Topical Subject
Extent
66 pages
Language
eng
Copyright Statement
In Copyright
Primary Member of
Peer-reviewed
No
Open Access
No
Handle
https://hdl.handle.net/2286/R.2.N.171676
Level of coding
minimal
Cataloging Standards
Note
Partial requirement for: M.S., Arizona State University, 2022
Field of study: Biology
System Created
- 2022-12-20 06:19:18
System Modified
- 2022-12-20 06:19:18
- 1 year 10 months ago
Additional Formats