Full metadata
Title
SRC Dependent EGFRvIII-STAT5 Activation Drives Resistance of Glioblastoma Cells
Description
Glioblastoma (GBM) is the most lethal primary brain tumor in adults with a less than 5% chance of survival beyond 5 years. With few effective therapies beyond the standard of care, there are often treatment resistant recurrences seen in most patients. STAT5 is a protein that has shown to be upregulated in highly invasive and treatment resistant GBM. Elucidating the role of STAT5 in GBM could reveal a node of therapeutic vulnerability in primary and recurrent GBM.
Date Created
2022-05
Contributors
- Inforzato, Hannah (Author)
- Plaisier, Christopher (Thesis director)
- Tran, Nhan (Committee member)
- Blomquist, Mylan (Committee member)
- Barrett, The Honors College (Contributor)
- School of Life Sciences (Contributor)
- Department of Psychology (Contributor)
Topical Subject
Resource Type
Copyright Statement
In Copyright
Primary Member of
Peer-reviewed
No
Open Access
No
Series
Academic Year 2021-2022
Handle
https://hdl.handle.net/2286/R.2.N.165469
System Created
- 2022-04-22 10:53:41
System Modified
- 2023-01-10 11:47:14
- 1 year 10 months ago
Additional Formats