Full metadata
Title
Gold nanorod-based assemblies and composites: cancer therapeutics, sensors and tissue engineering materials
Description
Gold nanoparticles as potential diagnostic, therapeutic and sensing systems have a long history of use in medicine, and have expanded to a variety of applications. Gold nanoparticles are attractive in biological applications due to their unique optical, chemical and biological properties. Particularly, gold nanorods (GNRs) are increasingly used due to superior optical property in the near infrared (NIR) window. Light absorbed by the nanorod can be dissipated as heat efficiently or re-emitted by the particle. However, the limitations for clinical translation of gold nanorods include low yields, poor stability, depth-restricted imaging, and resistance of cancer cells to hyperthermia, are severe. A novel high-throughput synthesis method was employed to significantly increase in yields of solid and porous gold nanorods/wires. Stable functional nanoassemblies and nanomaterials were generated by interfacing gold nanorods with a variety of polymeric and polypeptide-based coatings, resulting in unique properties of polymer-gold nanorod assemblies and composites. Here the use of these modified gold nanorods in a variety of applications including optical sensors, cancer therapeutics, and nanobiomaterials were described.
Date Created
2012
Contributors
- Huang, Huang-Chiao (Author)
- Rege, Kaushal (Thesis advisor)
- Sierks, Michael (Committee member)
- Dai, Lenore (Committee member)
- Ramakrishna, B (Committee member)
- Vogt, Bryan (Committee member)
- Arizona State University (Publisher)
Topical Subject
Resource Type
Extent
xiii, 236 p. : ill. (some col.)
Language
eng
Copyright Statement
In Copyright
Primary Member of
Peer-reviewed
No
Open Access
No
Handle
https://hdl.handle.net/2286/R.I.14615
Statement of Responsibility
by Huang-Chiao Huang
Description Source
Viewed on Feb. 20, 2013
Level of coding
full
Note
thesis
Partial requirement for: Ph.D., Arizona State University, 2012
bibliography
Includes bibliographical references (p. 202-231)
Field of study: Chemical engineering
System Created
- 2012-08-24 06:17:15
System Modified
- 2021-08-30 01:48:20
- 3 years 2 months ago
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