Description
A novel and unconventional approach for delivering a eukaryotic apoptosis factor, TNF-related apoptosis-inducing ligand (TRAIL), to cancer cells within and around necrotizing tumors by utilizing a S. Typhimurium purine requiring auxotroph as a biological vector to develop two anticancer therapies with multiple modality and broad economic feasibility.
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Details
Title
- Genetically Engineered Salmonella Typhimurium for Targeting & Selective Expression of TRAIL in Necrotizing Tumors
Contributors
Agent
- Koons, Andrew (Author)
- Curtiss, Roy (Thesis director)
- Lake, Douglas (Committee member)
- Janthakahalli, Nagaraj Vinay (Committee member)
- Barrett, The Honors College (Contributor)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2013-12
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