Full metadata
Title
The Effects of a Pesticide and Maturation on the Honeybee (Apis mellifera) blood-brain barrier
Description
Honeybees (Apis mellifera) are pollinators that face multiple challenges during foraging such as fungicides applied to floral sources. Fungicides are chemicals used to inhibit key fungal mechanisms like metabolism, but their effects remain relatively unknown in bees. In addition, studying the maturing bee can help us identify demographics that are more vulnerable to toxic materials like fungicides. The purpose of this study is test whether maturation and the fungicide Pristine influence the permeability of the blood-brain barrier. Specifically, we use a transportable dye to test how blood brain barrier transporter function responds to toxic insult and how it changes with age. Oral ingestion of Pristine by female workers did not have an effect on blood brain barrier permeability which suggests Pristine may have no or longer term consequences in the bee. However, blood brain barrier permeability changed with the bee's age which could be explained by the regulation of blood brain barrier transporters during natural transitions in hive task or the presence of hemolymph protein filtration
Date Created
2018-05
Contributors
- Patel, Aamir S. (Author)
- Amdam, Gro (Thesis director)
- Harrison, Jon (Committee member)
- Ozturk, Cahit (Committee member)
- School of Life Sciences (Contributor)
- Barrett, The Honors College (Contributor)
Topical Subject
Resource Type
Extent
15 pages
Language
eng
Copyright Statement
In Copyright
Primary Member of
Series
Academic Year 2017-2018
Handle
https://hdl.handle.net/2286/R.I.46699
Level of coding
minimal
Cataloging Standards
System Created
- 2018-03-24 12:00:02
System Modified
- 2021-08-11 04:09:57
- 3 years 3 months ago
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