Description
There is an increasing interest in developing thermo-responsive polymers for treating aneurysms. In this thesis project, the potential for poly(NIPAAm-co-JAAm-co-HEMA-Acrylate) (PNJHAc) as a treatment method for brain aneurysms was investigated. Five different batches of polymer were synthesized, purified, lyophilized, and characterized using nuclear magnetic resonance and cloud point techniques over the course of several months. Two were tested in aneurysm models. Of these five batches, there were two that showed promise as liquid embolic agents for endovascular embolization.
Details
Title
- Thermo-Responsive poly(N-isopropylacrylamide)-Based Polymers for Endovascular Brain Aneurysm Repair
Contributors
- Loui, Michelle (Author)
- Vernon, Brent (Thesis director)
- Pal, Amrita (Committee member)
- Harrington Bioengineering Program (Contributor, Contributor)
- Barrett, The Honors College (Contributor)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2020-05
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